Cardiopulmonary bypass in the pediatric population
Cardiopulmonary bypass (CPB) facilitates the repair of cardiac lesions in adults and children. Surgical mortality has decreased with improvements in technique allowing for the successful repair of complex heart defects in neonates of increasingly low body weight and gestational age. The physiologica...
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| Published in | Best practice & research. Clinical anaesthesiology Vol. 29; no. 2; pp. 241 - 256 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
Elsevier Ltd
01.06.2015
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| Abstract | Cardiopulmonary bypass (CPB) facilitates the repair of cardiac lesions in adults and children. Surgical mortality has decreased with improvements in technique allowing for the successful repair of complex heart defects in neonates of increasingly low body weight and gestational age. The physiological effects of CPB are more significant in children. The presence of intracardiac shunts and other anatomic variants further complicates CPB in patients with congenital heart disease. Special techniques and monitors are often necessary. Protocols are often established within individual institutions to standardize the approach to CPB. The anesthesiologist caring for the patient must understand the physiology of CPB to facilitate the initiation and separation from bypass, and to be able to treat complications. Evidence supporting a particular technique of CPB in pediatric population is still largely from uncontrolled or nonrandomized trials, observational studies, extrapolation from adult studies, and expert opinion. The heterogeneity of congenital heart disease makes randomized controlled trials or meta-analyses challenging, and thus they are limited in the literature. |
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| AbstractList | Cardiopulmonary bypass (CPB) facilitates the repair of cardiac lesions in adults and children. Surgical mortality has decreased with improvements in technique allowing for the successful repair of complex heart defects in neonates of increasingly low body weight and gestational age. The physiological effects of CPB are more significant in children. The presence of intracardiac shunts and other anatomic variants further complicates CPB in patients with congenital heart disease. Special techniques and monitors are often necessary. Protocols are often established within individual institutions to standardize the approach to CPB. The anesthesiologist caring for the patient must understand the physiology of CPB to facilitate the initiation and separation from bypass, and to be able to treat complications. Evidence supporting a particular technique of CPB in pediatric population is still largely from uncontrolled or nonrandomized trials, observational studies, extrapolation from adult studies, and expert opinion. The heterogeneity of congenital heart disease makes randomized controlled trials or meta-analyses challenging, and thus they are limited in the literature. |
| Author | DiNardo, James A., M.D Yuki, Koichi, M.D Whiting, David, M.D |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26060033$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/S0022-5223(03)00711-6 10.1213/01.ANE.0000072545.13681.FA 10.1051/ject/201143079 10.1177/1089253214526646 10.1053/j.jvca.2004.01.016 10.1111/pan.12560 10.1016/S0003-4975(00)02024-5 10.1191/0267659102pf595oa 10.1007/BF02097155 10.1016/S0003-4975(00)01752-5 10.1016/j.athoracsur.2012.05.135 10.1067/mtc.2001.112207 10.1016/S1053-0770(99)90268-9 10.1111/j.1460-9592.2004.01366.x 10.1016/j.jacc.2010.06.046 10.1016/S1010-7940(99)00301-2 10.1213/00000539-199705000-00008 10.1093/bja/43.12.1113 10.1097/00000658-195113440-00017 10.1161/01.CIR.92.9.490 10.1542/peds.2011-2034 10.1016/S0022-5223(97)70013-8 10.1016/j.athoracsur.2010.11.005 10.1213/01.ANE.0000134808.52676.4D 10.1016/S0022-5223(96)70374-4 10.1016/0003-4975(96)00324-4 10.1213/01.ane.0000297290.03501.db 10.1213/00000539-199205000-00003 10.1161/01.STR.20.7.904 10.1111/pan.12572 10.1002/ana.410190202 10.1016/j.jtcvs.2006.05.059 10.1177/021849230401200208 10.1056/NEJMoa041065 10.1016/j.jtcvs.2006.11.029 10.1016/j.jtcvs.2013.06.010 10.1161/CIRCULATIONAHA.108.830174 10.1016/S0003-4975(96)01017-X 10.1016/S0967-2109(98)00150-1 10.1097/ALN.0000000000000570 10.1111/j.1460-9592.2006.02029.x 10.1097/00000539-200106000-00006 10.1016/j.jtcvs.2007.03.067 10.1055/s-0037-1613757 10.1016/j.athoracsur.2005.03.062 |
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| Keywords | cardiopulmonary bypass congenital heart disease ultrafiltration |
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| References | Chauhan, Das, Bisoi (bib45) 2004; 18 Reid, Zimmerman, Laussen (bib47) 1997; 84 Chew, Brix-Christensen, Ravn (bib9) 2002; 17 Wypij, Jonas, Bellinger (bib6) 2008; 135 Bellinger, Wypij, duPlessis (bib32) 2003; 126 Xiong, Sun, Ji (bib12) 2015; 25 Mou, Giroir, Molitor-Kirsch (bib5) 2004; 351 Matte, Kussman, Wagner (bib52) 2011; 43 DiNardo (bib16) 2015; 25 Graham, Atz, McHugh (bib34) 2014; 147 Goldberg, Bove, Devaney (bib28) 2007; 133 Diesh, Flynn, Marable (bib22) 1957; 42 Rothman, Olney (bib19) 1986; 19 Birdi, Caputo, Underwood (bib15) 1999; 16 Andropoulos, Stayer, Diaz (bib26) 2004; 99 Hirsch, Jacobs, Andropoulos (bib27) 2012; 94 Gravlee (bib17) 2007 Gibbon (bib4) 1954; 37 Levin, Wu, Devine (bib48) 2000; 83 Mate (bib11) 2015 Bulutcu, Ozbek, Polat (bib50) 2005; 15 Clarizia, Manlhiot, Schwartz (bib35) 2011; 91 Pigula, Siewers, Nemoto (bib20) 2001; 121 Chauhan, Kumar, Rao (bib44) 2000; 70 Huyzen, van Oeveren, Wei (bib36) 1996; 62 Dennis, Spreng, Nelson (bib3) 1951; 134 Birdi, Caputo, Underwood (bib14) 1999; 7 Williams, Bratton, Riley (bib42) 1999; 13 Rahn (bib29) 1974; 151 Clowes, Neville, Sabga (bib23) 1958; 44 Zonis, Seear, Reichert (bib46) 1996; 111 Gruenwald, Manlhiot, Chan (bib38) 2010; 56 Taylor, Burrows, Bissonnette (bib21) 1992; 74 Pasquali, Li, He (bib33) 2012; 129 Chauhan, Bisoi, Kumar (bib49) 2004; 12 Wesley, Pereira, Scharp (bib41) 2015; 122 Mukherji, Hood, Edelstein (bib51) 2014; 18 Kirshbom, Skaryak, DiBernardo (bib24) 1995; 92 Trivedi, Patel, Turtle (bib30) 1997; 63 Harris, Seelye, Squire (bib25) 1971; 43 Seifert, Jobes, Ten Have (bib40) 2003; 97 Nagashima, Imai, Seo (bib10) 2000; 70 Heres, Speight, Benckart (bib39) 2001; 92 Caputo, Bays, Rogers (bib13) 2005; 80 Stoney (bib2) 2009; 119 Busto, Globus, Dietrich (bib18) 1989; 20 Baum (bib1) 2006; 16 Williams, Ramamoorthy, Chu (bib7) 2006; 132 Rao, Saxena, Chauhan (bib43) 2000; 111 Guzzetta, Bajaj, Fazlollah (bib37) 2008; 106 Naik, Knight, Elliott (bib8) 1991; 84 du Plessis, Jonas, Wypij (bib31) 1997; 114 Harris (10.1016/j.bpa.2015.03.006_bib25) 1971; 43 Birdi (10.1016/j.bpa.2015.03.006_bib15) 1999; 16 Chauhan (10.1016/j.bpa.2015.03.006_bib44) 2000; 70 Bulutcu (10.1016/j.bpa.2015.03.006_bib50) 2005; 15 Stoney (10.1016/j.bpa.2015.03.006_bib2) 2009; 119 Chew (10.1016/j.bpa.2015.03.006_bib9) 2002; 17 Heres (10.1016/j.bpa.2015.03.006_bib39) 2001; 92 du Plessis (10.1016/j.bpa.2015.03.006_bib31) 1997; 114 Matte (10.1016/j.bpa.2015.03.006_bib52) 2011; 43 Rahn (10.1016/j.bpa.2015.03.006_bib29) 1974; 151 Guzzetta (10.1016/j.bpa.2015.03.006_bib37) 2008; 106 Zonis (10.1016/j.bpa.2015.03.006_bib46) 1996; 111 Rothman (10.1016/j.bpa.2015.03.006_bib19) 1986; 19 Mou (10.1016/j.bpa.2015.03.006_bib5) 2004; 351 Clarizia (10.1016/j.bpa.2015.03.006_bib35) 2011; 91 Clowes (10.1016/j.bpa.2015.03.006_bib23) 1958; 44 Trivedi (10.1016/j.bpa.2015.03.006_bib30) 1997; 63 Andropoulos (10.1016/j.bpa.2015.03.006_bib26) 2004; 99 Levin (10.1016/j.bpa.2015.03.006_bib48) 2000; 83 Chauhan (10.1016/j.bpa.2015.03.006_bib49) 2004; 12 Xiong (10.1016/j.bpa.2015.03.006_bib12) 2015; 25 Dennis (10.1016/j.bpa.2015.03.006_bib3) 1951; 134 Bellinger (10.1016/j.bpa.2015.03.006_bib32) 2003; 126 Mukherji (10.1016/j.bpa.2015.03.006_bib51) 2014; 18 Taylor (10.1016/j.bpa.2015.03.006_bib21) 1992; 74 Graham (10.1016/j.bpa.2015.03.006_bib34) 2014; 147 Chauhan (10.1016/j.bpa.2015.03.006_bib45) 2004; 18 Nagashima (10.1016/j.bpa.2015.03.006_bib10) 2000; 70 Birdi (10.1016/j.bpa.2015.03.006_bib14) 1999; 7 Naik (10.1016/j.bpa.2015.03.006_bib8) 1991; 84 Gibbon (10.1016/j.bpa.2015.03.006_bib4) 1954; 37 DiNardo (10.1016/j.bpa.2015.03.006_bib16) 2015; 25 Goldberg (10.1016/j.bpa.2015.03.006_bib28) 2007; 133 Reid (10.1016/j.bpa.2015.03.006_bib47) 1997; 84 Caputo (10.1016/j.bpa.2015.03.006_bib13) 2005; 80 Wypij (10.1016/j.bpa.2015.03.006_bib6) 2008; 135 Hirsch (10.1016/j.bpa.2015.03.006_bib27) 2012; 94 Pigula (10.1016/j.bpa.2015.03.006_bib20) 2001; 121 Rao (10.1016/j.bpa.2015.03.006_bib43) 2000; 111 Mate (10.1016/j.bpa.2015.03.006_bib11) 2015 Gravlee (10.1016/j.bpa.2015.03.006_bib17) 2007 Huyzen (10.1016/j.bpa.2015.03.006_bib36) 1996; 62 Kirshbom (10.1016/j.bpa.2015.03.006_bib24) 1995; 92 Wesley (10.1016/j.bpa.2015.03.006_bib41) 2015; 122 Williams (10.1016/j.bpa.2015.03.006_bib42) 1999; 13 Gruenwald (10.1016/j.bpa.2015.03.006_bib38) 2010; 56 Seifert (10.1016/j.bpa.2015.03.006_bib40) 2003; 97 Busto (10.1016/j.bpa.2015.03.006_bib18) 1989; 20 Williams (10.1016/j.bpa.2015.03.006_bib7) 2006; 132 Pasquali (10.1016/j.bpa.2015.03.006_bib33) 2012; 129 Diesh (10.1016/j.bpa.2015.03.006_bib22) 1957; 42 Baum (10.1016/j.bpa.2015.03.006_bib1) 2006; 16 |
| References_xml | – volume: 56 start-page: 1794 year: 2010 end-page: 1802 ident: bib38 article-title: Randomized, controlled trial of individualized heparin and protamine management in infants undergoing cardiac surgery with cardiopulmonary bypass publication-title: J Am Coll Cardiol contributor: fullname: Chan – volume: 119 start-page: 2844 year: 2009 end-page: 2853 ident: bib2 article-title: Evolution of cardiopulmonary bypass publication-title: Circulation contributor: fullname: Stoney – volume: 19 start-page: 105 year: 1986 end-page: 111 ident: bib19 article-title: Glutamate and the pathophysiology of hypoxic–ischemic brain damage publication-title: Ann Neurol contributor: fullname: Olney – volume: 63 start-page: 167 year: 1997 end-page: 174 ident: bib30 article-title: Relative changes in cerebral blood flow during cardiac operations using xenon-133 clearance versus transcranial Doppler sonography publication-title: Ann Thorac Surg contributor: fullname: Turtle – volume: 16 start-page: 1213 year: 2006 end-page: 1225 ident: bib1 article-title: Pediatric cardiac surgery: an historical appreciation publication-title: Paediatr Anaesth contributor: fullname: Baum – volume: 62 start-page: 533 year: 1996 end-page: 537 ident: bib36 article-title: In vitro effect of hemodilution on activated clotting time and high-dose thrombin time during cardiopulmonary bypass publication-title: Ann Thorac Surg contributor: fullname: Wei – volume: 114 start-page: 991 year: 1997 end-page: 1000 ident: bib31 article-title: Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants publication-title: J Thorac Cardiovasc Surg contributor: fullname: Wypij – volume: 92 start-page: II490 year: 1995 end-page: II494 ident: bib24 article-title: Effects of aortopulmonary collaterals on cerebral cooling and cerebral metabolic recovery after circulatory arrest publication-title: Circulation contributor: fullname: DiBernardo – volume: 18 start-page: 190 year: 2014 end-page: 207 ident: bib51 article-title: Overcoming challenges in the management of critical events during cardiopulmonary bypass publication-title: Semin Cardiothorac Vasc Anesth contributor: fullname: Edelstein – volume: 18 start-page: 141 year: 2004 end-page: 143 ident: bib45 article-title: Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery publication-title: J Cardiothorac Vasc Anesth contributor: fullname: Bisoi – volume: 111 start-page: 982 year: 1996 end-page: 987 ident: bib46 article-title: The effect of preoperative tranexamic acid on blood loss after cardiac operations in children publication-title: J Thorac Cardiovasc Surg contributor: fullname: Reichert – year: 2007 ident: bib17 article-title: Cardiopumonary bypass: principles and practice contributor: fullname: Gravlee – volume: 151 start-page: 87 year: 1974 end-page: 94 ident: bib29 article-title: Body temperature and acid-base regulation. (Review article) publication-title: Pneumonol Pneumonol contributor: fullname: Rahn – volume: 132 start-page: 1291 year: 2006 end-page: 1298 ident: bib7 article-title: Modified and conventional ultrafiltration during pediatric cardiac surgery: clinical outcomes compared publication-title: J Thorac Cardiovasc Surg contributor: fullname: Chu – volume: 80 start-page: 982 year: 2005 end-page: 988 ident: bib13 article-title: Randomized comparison between normothermic and hypothermic cardiopulmonary bypass in pediatric open-heart surgery publication-title: Ann Thorac Surg contributor: fullname: Rogers – volume: 126 start-page: 1385 year: 2003 end-page: 1396 ident: bib32 article-title: Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston circulatory arrest trial publication-title: J Thorac Cardiovasc Surg contributor: fullname: duPlessis – volume: 92 start-page: 1391 year: 2001 end-page: 1395 ident: bib39 article-title: The clinical onset of heparin is rapid publication-title: Anesth Analg contributor: fullname: Benckart – volume: 42 start-page: 67 year: 1957 end-page: 72 ident: bib22 article-title: Comparison of low (azygous) flow and high flow principles of extracorporeal circulation employing a bubble oxygenator publication-title: Surgery contributor: fullname: Marable – volume: 70 start-page: 1308 year: 2000 end-page: 1312 ident: bib44 article-title: Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease publication-title: Ann Thorac Surg contributor: fullname: Rao – volume: 351 start-page: 1635 year: 2004 end-page: 1644 ident: bib5 article-title: Fresh whole blood versus reconstituted blood for pump priming in heart surgery in infants publication-title: N Engl J Med contributor: fullname: Molitor-Kirsch – volume: 94 start-page: 1365 year: 2012 end-page: 1373 ident: bib27 article-title: Protecting the infant brain during cardiac surgery: a systematic review publication-title: Ann Thorac Surg contributor: fullname: Andropoulos – volume: 37 start-page: 171 year: 1954 end-page: 185 ident: bib4 article-title: Application of a mechanical heart and lung apparatus to cardiac surgery publication-title: Minn Med contributor: fullname: Gibbon – volume: 13 start-page: 304 year: 1999 end-page: 308 ident: bib42 article-title: Efficacy of epsilon-aminocaproic acid in children undergoing cardiac surgery publication-title: J Cardiothorac Vasc Anesth contributor: fullname: Riley – volume: 74 start-page: 636 year: 1992 end-page: 642 ident: bib21 article-title: Cerebral pressure-flow velocity relationship during hypothermic cardiopulmonary bypass in neonates and infants publication-title: Anesth Analg contributor: fullname: Bissonnette – volume: 133 start-page: 880 year: 2007 end-page: 887 ident: bib28 article-title: A randomized clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: outcomes for infants with functional single ventricle publication-title: J Thorac Cardiovasc Surg contributor: fullname: Devaney – volume: 70 start-page: 1901 year: 2000 end-page: 1906 ident: bib10 article-title: Effect of hemofiltrated whole blood pump priming on hemodynamics and respiratory function after the arterial switch operation in neonates publication-title: Ann Thorac Surg contributor: fullname: Seo – volume: 135 start-page: 355 year: 2008 end-page: 360 ident: bib6 article-title: The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: results from the combined Boston hematocrit trials publication-title: J Thorac Cardiovasc Surg contributor: fullname: Bellinger – volume: 83 start-page: 54 year: 2000 end-page: 59 ident: bib48 article-title: Hemostatic parameters and platelet activation marker expression in cyanotic and acyanotic pediatric patients undergoing cardiac surgery in the presence of tranexamic acid publication-title: Thromb Haemost contributor: fullname: Devine – volume: 91 start-page: 1222 year: 2011 end-page: 1227 ident: bib35 article-title: Improved outcomes associated with intraoperative steroid use in high-risk pediatric cardiac surgery publication-title: Ann Thorac Surg contributor: fullname: Schwartz – volume: 20 start-page: 904 year: 1989 end-page: 910 ident: bib18 article-title: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain publication-title: Stroke J Cereb Circ contributor: fullname: Dietrich – volume: 44 start-page: 220 year: 1958 end-page: 239 ident: bib23 article-title: The relationship of oxygen consumption, perfusion rate, and temperature to the acidosis associated with cardiopulmonary circulatory bypass publication-title: Surgery contributor: fullname: Sabga – volume: 84 start-page: 990 year: 1997 end-page: 996 ident: bib47 article-title: The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery publication-title: Anesth Analg contributor: fullname: Laussen – volume: 121 start-page: 366 year: 2001 end-page: 373 ident: bib20 article-title: Hypothermic cardiopulmonary bypass alters oxygen/glucose uptake in the pediatric brain publication-title: J Thorac Cardiovasc Surg contributor: fullname: Nemoto – volume: 99 start-page: 1365 year: 2004 end-page: 1375 ident: bib26 article-title: Neurological monitoring for congenital heart surgery publication-title: Anesth Analg contributor: fullname: Diaz – volume: 84 start-page: III422 year: 1991 end-page: III431 ident: bib8 article-title: A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery publication-title: Circulation contributor: fullname: Elliott – volume: 17 start-page: 327 year: 2002 end-page: 333 ident: bib9 article-title: Effect of modified ultrafiltration on the inflammatory response in paediatric open-heart surgery: a prospective, randomized study publication-title: Perfusion contributor: fullname: Ravn – volume: 25 start-page: 135 year: 2015 end-page: 142 ident: bib12 article-title: Systematic review and meta-analysis of benefits and risks between normothermia and hypothermia during cardiopulmonary bypass in pediatric cardiac surgery publication-title: Paediatr Anaesth contributor: fullname: Ji – volume: 15 start-page: 41 year: 2005 end-page: 46 ident: bib50 article-title: Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination? publication-title: Paediatr Anaesth contributor: fullname: Polat – volume: 106 start-page: 419 year: 2008 end-page: 425 ident: bib37 article-title: A comparison of heparin management strategies in infants undergoing cardiopulmonary bypass publication-title: Anesth Analg contributor: fullname: Fazlollah – volume: 7 start-page: 369 year: 1999 end-page: 374 ident: bib14 article-title: Influence of normothermic systemic perfusion temperature on cold myocardial protection during coronary artery bypass surgery publication-title: Cardiovasc Surg contributor: fullname: Underwood – volume: 111 start-page: 57 year: 2000 end-page: 61 ident: bib43 article-title: Epsilon aminocaproic acid in paediatric cardiac surgery to reduce postoperative blood loss publication-title: Indian J Med Res contributor: fullname: Chauhan – volume: 129 start-page: e385 year: 2012 end-page: e391 ident: bib33 article-title: Perioperative methylprednisolone and outcome in neonates undergoing heart surgery publication-title: Pediatrics contributor: fullname: He – volume: 25 start-page: 111 year: 2015 end-page: 112 ident: bib16 article-title: Normothermic CPB for pediatric cardiac surgery, not ready for prime time publication-title: Paediatr Anaesth contributor: fullname: DiNardo – volume: 122 start-page: 746 year: 2015 end-page: 758 ident: bib41 article-title: Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass publication-title: Anesthesiology contributor: fullname: Scharp – volume: 134 start-page: 709 year: 1951 end-page: 721 ident: bib3 article-title: Development of a pump-oxygenator to replace the heart and lungs; an apparatus applicable to human patients, and application to one case publication-title: Ann Surg contributor: fullname: Nelson – year: 2015 ident: bib11 article-title: Perfusion for congenital heart surgery: notes on cardiopulmonary bypass for a complex patient population contributor: fullname: Mate – volume: 147 start-page: 902 year: 2014 end-page: 908 ident: bib34 article-title: Preoperative steroid treatment does not improve markers of inflammation after cardiac surgery in neonates: results from a randomized trial publication-title: J Thorac Cardiovasc Surg contributor: fullname: McHugh – volume: 12 start-page: 121 year: 2004 end-page: 124 ident: bib49 article-title: Dose comparison of tranexamic acid in pediatric cardiac surgery publication-title: Asian Cardiovasc Thorac Ann contributor: fullname: Kumar – volume: 43 start-page: 1113 year: 1971 end-page: 1120 ident: bib25 article-title: Oxygen consumption during cardiopulmonary bypass with moderate hypothermia in man publication-title: Br J Anaesth contributor: fullname: Squire – volume: 16 start-page: 540 year: 1999 end-page: 545 ident: bib15 article-title: The effects of cardiopulmonary bypass temperature on inflammatory response following cardiopulmonary bypass publication-title: Eur J Cardio Thorac Surg – Off J Eur Assoc Cardio Thorac Surg contributor: fullname: Underwood – volume: 97 start-page: 383 year: 2003 end-page: 389 ident: bib40 article-title: Adverse events after protamine administration following cardiopulmonary bypass in infants and children publication-title: Anesth Analg contributor: fullname: Ten Have – volume: 43 start-page: 79 year: 2011 end-page: 83 ident: bib52 article-title: Massive air embolism in a Fontan patient publication-title: J Extra Corpor Technol contributor: fullname: Wagner – volume: 126 start-page: 1385 year: 2003 ident: 10.1016/j.bpa.2015.03.006_bib32 article-title: Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston circulatory arrest trial publication-title: J Thorac Cardiovasc Surg doi: 10.1016/S0022-5223(03)00711-6 contributor: fullname: Bellinger – volume: 97 start-page: 383 year: 2003 ident: 10.1016/j.bpa.2015.03.006_bib40 article-title: Adverse events after protamine administration following cardiopulmonary bypass in infants and children publication-title: Anesth Analg doi: 10.1213/01.ANE.0000072545.13681.FA contributor: fullname: Seifert – volume: 37 start-page: 171 year: 1954 ident: 10.1016/j.bpa.2015.03.006_bib4 article-title: Application of a mechanical heart and lung apparatus to cardiac surgery publication-title: Minn Med contributor: fullname: Gibbon – volume: 43 start-page: 79 year: 2011 ident: 10.1016/j.bpa.2015.03.006_bib52 article-title: Massive air embolism in a Fontan patient publication-title: J Extra Corpor Technol doi: 10.1051/ject/201143079 contributor: fullname: Matte – volume: 18 start-page: 190 year: 2014 ident: 10.1016/j.bpa.2015.03.006_bib51 article-title: Overcoming challenges in the management of critical events during cardiopulmonary bypass publication-title: Semin Cardiothorac Vasc Anesth doi: 10.1177/1089253214526646 contributor: fullname: Mukherji – volume: 18 start-page: 141 year: 2004 ident: 10.1016/j.bpa.2015.03.006_bib45 article-title: Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery publication-title: J Cardiothorac Vasc Anesth doi: 10.1053/j.jvca.2004.01.016 contributor: fullname: Chauhan – volume: 25 start-page: 135 year: 2015 ident: 10.1016/j.bpa.2015.03.006_bib12 article-title: Systematic review and meta-analysis of benefits and risks between normothermia and hypothermia during cardiopulmonary bypass in pediatric cardiac surgery publication-title: Paediatr Anaesth doi: 10.1111/pan.12560 contributor: fullname: Xiong – volume: 70 start-page: 1901 year: 2000 ident: 10.1016/j.bpa.2015.03.006_bib10 article-title: Effect of hemofiltrated whole blood pump priming on hemodynamics and respiratory function after the arterial switch operation in neonates publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(00)02024-5 contributor: fullname: Nagashima – volume: 17 start-page: 327 year: 2002 ident: 10.1016/j.bpa.2015.03.006_bib9 article-title: Effect of modified ultrafiltration on the inflammatory response in paediatric open-heart surgery: a prospective, randomized study publication-title: Perfusion doi: 10.1191/0267659102pf595oa contributor: fullname: Chew – volume: 44 start-page: 220 year: 1958 ident: 10.1016/j.bpa.2015.03.006_bib23 article-title: The relationship of oxygen consumption, perfusion rate, and temperature to the acidosis associated with cardiopulmonary circulatory bypass publication-title: Surgery contributor: fullname: Clowes – volume: 151 start-page: 87 year: 1974 ident: 10.1016/j.bpa.2015.03.006_bib29 article-title: Body temperature and acid-base regulation. (Review article) publication-title: Pneumonol Pneumonol doi: 10.1007/BF02097155 contributor: fullname: Rahn – volume: 70 start-page: 1308 year: 2000 ident: 10.1016/j.bpa.2015.03.006_bib44 article-title: Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(00)01752-5 contributor: fullname: Chauhan – volume: 94 start-page: 1365 year: 2012 ident: 10.1016/j.bpa.2015.03.006_bib27 article-title: Protecting the infant brain during cardiac surgery: a systematic review publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2012.05.135 contributor: fullname: Hirsch – volume: 84 start-page: III422 year: 1991 ident: 10.1016/j.bpa.2015.03.006_bib8 article-title: A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery publication-title: Circulation contributor: fullname: Naik – volume: 121 start-page: 366 year: 2001 ident: 10.1016/j.bpa.2015.03.006_bib20 article-title: Hypothermic cardiopulmonary bypass alters oxygen/glucose uptake in the pediatric brain publication-title: J Thorac Cardiovasc Surg doi: 10.1067/mtc.2001.112207 contributor: fullname: Pigula – volume: 13 start-page: 304 year: 1999 ident: 10.1016/j.bpa.2015.03.006_bib42 article-title: Efficacy of epsilon-aminocaproic acid in children undergoing cardiac surgery publication-title: J Cardiothorac Vasc Anesth doi: 10.1016/S1053-0770(99)90268-9 contributor: fullname: Williams – volume: 15 start-page: 41 year: 2005 ident: 10.1016/j.bpa.2015.03.006_bib50 article-title: Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination? publication-title: Paediatr Anaesth doi: 10.1111/j.1460-9592.2004.01366.x contributor: fullname: Bulutcu – volume: 56 start-page: 1794 year: 2010 ident: 10.1016/j.bpa.2015.03.006_bib38 article-title: Randomized, controlled trial of individualized heparin and protamine management in infants undergoing cardiac surgery with cardiopulmonary bypass publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2010.06.046 contributor: fullname: Gruenwald – volume: 16 start-page: 540 year: 1999 ident: 10.1016/j.bpa.2015.03.006_bib15 article-title: The effects of cardiopulmonary bypass temperature on inflammatory response following cardiopulmonary bypass publication-title: Eur J Cardio Thorac Surg – Off J Eur Assoc Cardio Thorac Surg doi: 10.1016/S1010-7940(99)00301-2 contributor: fullname: Birdi – volume: 84 start-page: 990 year: 1997 ident: 10.1016/j.bpa.2015.03.006_bib47 article-title: The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery publication-title: Anesth Analg doi: 10.1213/00000539-199705000-00008 contributor: fullname: Reid – volume: 111 start-page: 57 year: 2000 ident: 10.1016/j.bpa.2015.03.006_bib43 article-title: Epsilon aminocaproic acid in paediatric cardiac surgery to reduce postoperative blood loss publication-title: Indian J Med Res contributor: fullname: Rao – volume: 43 start-page: 1113 year: 1971 ident: 10.1016/j.bpa.2015.03.006_bib25 article-title: Oxygen consumption during cardiopulmonary bypass with moderate hypothermia in man publication-title: Br J Anaesth doi: 10.1093/bja/43.12.1113 contributor: fullname: Harris – volume: 134 start-page: 709 year: 1951 ident: 10.1016/j.bpa.2015.03.006_bib3 article-title: Development of a pump-oxygenator to replace the heart and lungs; an apparatus applicable to human patients, and application to one case publication-title: Ann Surg doi: 10.1097/00000658-195113440-00017 contributor: fullname: Dennis – volume: 92 start-page: II490 year: 1995 ident: 10.1016/j.bpa.2015.03.006_bib24 article-title: Effects of aortopulmonary collaterals on cerebral cooling and cerebral metabolic recovery after circulatory arrest publication-title: Circulation doi: 10.1161/01.CIR.92.9.490 contributor: fullname: Kirshbom – volume: 129 start-page: e385 year: 2012 ident: 10.1016/j.bpa.2015.03.006_bib33 article-title: Perioperative methylprednisolone and outcome in neonates undergoing heart surgery publication-title: Pediatrics doi: 10.1542/peds.2011-2034 contributor: fullname: Pasquali – volume: 114 start-page: 991 year: 1997 ident: 10.1016/j.bpa.2015.03.006_bib31 article-title: Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants publication-title: J Thorac Cardiovasc Surg doi: 10.1016/S0022-5223(97)70013-8 contributor: fullname: du Plessis – volume: 91 start-page: 1222 year: 2011 ident: 10.1016/j.bpa.2015.03.006_bib35 article-title: Improved outcomes associated with intraoperative steroid use in high-risk pediatric cardiac surgery publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2010.11.005 contributor: fullname: Clarizia – volume: 99 start-page: 1365 year: 2004 ident: 10.1016/j.bpa.2015.03.006_bib26 article-title: Neurological monitoring for congenital heart surgery publication-title: Anesth Analg doi: 10.1213/01.ANE.0000134808.52676.4D contributor: fullname: Andropoulos – volume: 111 start-page: 982 year: 1996 ident: 10.1016/j.bpa.2015.03.006_bib46 article-title: The effect of preoperative tranexamic acid on blood loss after cardiac operations in children publication-title: J Thorac Cardiovasc Surg doi: 10.1016/S0022-5223(96)70374-4 contributor: fullname: Zonis – volume: 62 start-page: 533 year: 1996 ident: 10.1016/j.bpa.2015.03.006_bib36 article-title: In vitro effect of hemodilution on activated clotting time and high-dose thrombin time during cardiopulmonary bypass publication-title: Ann Thorac Surg doi: 10.1016/0003-4975(96)00324-4 contributor: fullname: Huyzen – year: 2007 ident: 10.1016/j.bpa.2015.03.006_bib17 contributor: fullname: Gravlee – volume: 106 start-page: 419 year: 2008 ident: 10.1016/j.bpa.2015.03.006_bib37 article-title: A comparison of heparin management strategies in infants undergoing cardiopulmonary bypass publication-title: Anesth Analg doi: 10.1213/01.ane.0000297290.03501.db contributor: fullname: Guzzetta – volume: 74 start-page: 636 year: 1992 ident: 10.1016/j.bpa.2015.03.006_bib21 article-title: Cerebral pressure-flow velocity relationship during hypothermic cardiopulmonary bypass in neonates and infants publication-title: Anesth Analg doi: 10.1213/00000539-199205000-00003 contributor: fullname: Taylor – volume: 20 start-page: 904 year: 1989 ident: 10.1016/j.bpa.2015.03.006_bib18 article-title: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain publication-title: Stroke J Cereb Circ doi: 10.1161/01.STR.20.7.904 contributor: fullname: Busto – volume: 25 start-page: 111 year: 2015 ident: 10.1016/j.bpa.2015.03.006_bib16 article-title: Normothermic CPB for pediatric cardiac surgery, not ready for prime time publication-title: Paediatr Anaesth doi: 10.1111/pan.12572 contributor: fullname: DiNardo – volume: 19 start-page: 105 year: 1986 ident: 10.1016/j.bpa.2015.03.006_bib19 article-title: Glutamate and the pathophysiology of hypoxic–ischemic brain damage publication-title: Ann Neurol doi: 10.1002/ana.410190202 contributor: fullname: Rothman – volume: 132 start-page: 1291 year: 2006 ident: 10.1016/j.bpa.2015.03.006_bib7 article-title: Modified and conventional ultrafiltration during pediatric cardiac surgery: clinical outcomes compared publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2006.05.059 contributor: fullname: Williams – volume: 12 start-page: 121 year: 2004 ident: 10.1016/j.bpa.2015.03.006_bib49 article-title: Dose comparison of tranexamic acid in pediatric cardiac surgery publication-title: Asian Cardiovasc Thorac Ann doi: 10.1177/021849230401200208 contributor: fullname: Chauhan – volume: 351 start-page: 1635 year: 2004 ident: 10.1016/j.bpa.2015.03.006_bib5 article-title: Fresh whole blood versus reconstituted blood for pump priming in heart surgery in infants publication-title: N Engl J Med doi: 10.1056/NEJMoa041065 contributor: fullname: Mou – year: 2015 ident: 10.1016/j.bpa.2015.03.006_bib11 contributor: fullname: Mate – volume: 133 start-page: 880 year: 2007 ident: 10.1016/j.bpa.2015.03.006_bib28 article-title: A randomized clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: outcomes for infants with functional single ventricle publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2006.11.029 contributor: fullname: Goldberg – volume: 147 start-page: 902 year: 2014 ident: 10.1016/j.bpa.2015.03.006_bib34 article-title: Preoperative steroid treatment does not improve markers of inflammation after cardiac surgery in neonates: results from a randomized trial publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2013.06.010 contributor: fullname: Graham – volume: 119 start-page: 2844 year: 2009 ident: 10.1016/j.bpa.2015.03.006_bib2 article-title: Evolution of cardiopulmonary bypass publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.830174 contributor: fullname: Stoney – volume: 63 start-page: 167 year: 1997 ident: 10.1016/j.bpa.2015.03.006_bib30 article-title: Relative changes in cerebral blood flow during cardiac operations using xenon-133 clearance versus transcranial Doppler sonography publication-title: Ann Thorac Surg doi: 10.1016/S0003-4975(96)01017-X contributor: fullname: Trivedi – volume: 42 start-page: 67 year: 1957 ident: 10.1016/j.bpa.2015.03.006_bib22 article-title: Comparison of low (azygous) flow and high flow principles of extracorporeal circulation employing a bubble oxygenator publication-title: Surgery contributor: fullname: Diesh – volume: 7 start-page: 369 year: 1999 ident: 10.1016/j.bpa.2015.03.006_bib14 article-title: Influence of normothermic systemic perfusion temperature on cold myocardial protection during coronary artery bypass surgery publication-title: Cardiovasc Surg doi: 10.1016/S0967-2109(98)00150-1 contributor: fullname: Birdi – volume: 122 start-page: 746 issue: 4 year: 2015 ident: 10.1016/j.bpa.2015.03.006_bib41 article-title: Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass publication-title: Anesthesiology doi: 10.1097/ALN.0000000000000570 contributor: fullname: Wesley – volume: 16 start-page: 1213 year: 2006 ident: 10.1016/j.bpa.2015.03.006_bib1 article-title: Pediatric cardiac surgery: an historical appreciation publication-title: Paediatr Anaesth doi: 10.1111/j.1460-9592.2006.02029.x contributor: fullname: Baum – volume: 92 start-page: 1391 year: 2001 ident: 10.1016/j.bpa.2015.03.006_bib39 article-title: The clinical onset of heparin is rapid publication-title: Anesth Analg doi: 10.1097/00000539-200106000-00006 contributor: fullname: Heres – volume: 135 start-page: 355 year: 2008 ident: 10.1016/j.bpa.2015.03.006_bib6 article-title: The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: results from the combined Boston hematocrit trials publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2007.03.067 contributor: fullname: Wypij – volume: 83 start-page: 54 year: 2000 ident: 10.1016/j.bpa.2015.03.006_bib48 article-title: Hemostatic parameters and platelet activation marker expression in cyanotic and acyanotic pediatric patients undergoing cardiac surgery in the presence of tranexamic acid publication-title: Thromb Haemost doi: 10.1055/s-0037-1613757 contributor: fullname: Levin – volume: 80 start-page: 982 year: 2005 ident: 10.1016/j.bpa.2015.03.006_bib13 article-title: Randomized comparison between normothermic and hypothermic cardiopulmonary bypass in pediatric open-heart surgery publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2005.03.062 contributor: fullname: Caputo |
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| Snippet | Cardiopulmonary bypass (CPB) facilitates the repair of cardiac lesions in adults and children. Surgical mortality has decreased with improvements in technique... |
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| SubjectTerms | Anesthesia & Perioperative Care Anesthesiology - methods Anesthesiology - trends cardiopulmonary bypass Cardiopulmonary Bypass - adverse effects Cardiopulmonary Bypass - methods Cardiopulmonary Bypass - trends Child congenital heart disease Heart Defects, Congenital - diagnosis Heart Defects, Congenital - epidemiology Heart Defects, Congenital - surgery Humans ultrafiltration |
| Title | Cardiopulmonary bypass in the pediatric population |
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