Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation - Domingues, Alison; Boisson-Vidal, Catherine; Marquet de Rouge, Perrine; Dizier, Blandine; Sadoine, Jérémy; Mignon, Virginie; Vessières, Emilie; Henrion, Daniel; Escriou, Virginie; Bigey, Pascal; Chaussain, Catherine; Smadja, David M.; et al. (Angiogenesis (London), 2020)
Keywords: Angiogenesis; Animal models; Animals; Aorta; Biomedical and Life Sciences; Biomedicine; Blood flow; Blood vessels; Cancer Research; Carbohydrates; Cardiology; Cardiology and cardiovascular system; Carrier Proteins - genetics; Cell Biology; Cells, Cultured; Cellular Biology; Complications; Cytoprotection - genetics; Diet; Endothelial cells; Endothelial Cells - physiology; High carbohydrate diet; High protein diet; Hindlimb - blood supply; Human health and pathology; Impairment; In vivo methods and tests; Ischemia; Ischemia - genetics; Ischemia - metabolism; Ischemia - physiopathology; Ischemia - prevention & control; Life Sciences; Low carbohydrate diet; Low protein diet; Male; Metabolic Diseases - complications; Metabolic Diseases - genetics; Metabolic Diseases - metabolism; Metabolic Diseases - physiopathology; Metabolic disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic - genetics; Nutrient deficiency; Oncology; Ophthalmology; Original Paper; Oxidative stress; Oxidative Stress - physiology; Proteins; siRNA; Subcellular Processes; Therapeutic applications; Thioredoxin; Thioredoxins - genetics; Endothelial dysfunction; Oxidative stress; TXNIP; Arterial damage; Metabolic disorders; Post-ischemic revascularisation