Vascular Dysfunction Is Central to Alzheimer’s Disease Pathogenesis in APOE e4 Carriers - McCorkindale, Andrew N.; Mundell, Hamish D.; Guennewig, Boris; Sutherland, Greg T. (International journal of molecular sciences, 2022)
Keywords: Algorithms; Alzheimer Disease - genetics; Alzheimer Disease - pathology; Alzheimer's disease; Apolipoprotein E4 - genetics; Apolipoproteins E - genetics; Apolipoproteins E - metabolism; Biobanks; Brain; Brain - diagnostic imaging; Brain - pathology; Cerebral Amyloid Angiopathy - genetics; Cerebral Amyloid Angiopathy - pathology; Datasets; Dementia; Feature selection; Females; Genotype & phenotype; Haplotypes; Heterozygote; Humans; Machine learning; Magnetic resonance imaging; Medical imaging; Neuropathology; Pathogenesis; Pathology; Variables; United Kingdom--UK; transcriptomics; tangles; cerebral amyloid angiopathy; UK Biobank; APOE4; plaques