Reconceptualization of Hormetic Responses in the Frame of Redox Toxicology

• Published in: International journal of molecular sciences Vol. 23; no. 1; p. 49
• Main Authors: Skaperda, Zoi, Tekos, Fotios, Vardakas, Periklis, Nepka, Charitini, Kouretas, Demetrios
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.12.2021; MDPI
• Subjects: Adaptation; Adaptation, Physiological - physiology; Animals; Antioxidants; Apoptosis; Bioactive compounds; Biocompatibility; Biomarkers; Biomarkers - metabolism; Chemical compounds; Dietary supplements; dose; duration of exposure; Enzymes; Exposure; Heterogeneity; Homeostasis; Hormesis; Hormesis - physiology; Humans; Metabolism; Olive oil; Oxidation-Reduction; Oxidative stress; Phenotypes; Phytochemicals; polyphenols; Radiation; redox biomarkers; Regulation; Review; Toxicology; Toxicology - methods; polyphenols; dose; hormesis; redox biomarkers; oxidative stress; duration of exposure

Cellular adaptive mechanisms emerging after exposure to low levels of toxic agents or stressful stimuli comprise an important biological feature that has gained considerable scientific interest. Investigations of low-dose exposures to diverse chemical compounds signify the non-linear mode of action...