Retinal nerve fiber layer and macular thickness in patients with schizophrenia: Influence of recent illness episodes

• Published in: Psychiatry research Vol. 229; no. 1-2; pp. 230 - 236
• Main Authors: Ascaso, Francisco J., Rodriguez-Jimenez, Roberto, Cabezón, Laura, López-Antón, Raúl, Santabárbara, Javier, De la Cámara, Concepción, Modrego, Pedro J., Quintanilla, Miguel A., Bagney, Alexandra, Gutierrez, Leticia, Cruz, Nancy, Cristóbal, José A., Lobo, Antonio
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 30.09.2015
• Subjects: Adult; Antipsychotic Agents - therapeutic use; Episode of Care; Female; Humans; Linear Models; Macula Lutea - drug effects; Macula Lutea - pathology; Male; Middle Aged; Nerve Fibers - drug effects; Nerve Fibers - pathology; Neuroimaging; OCT; Optical coherence tomography; Psychiatric Status Rating Scales; Psychiatry; Psychotic episode; Reference Values; Retina - drug effects; Retina - pathology; Retinal Ganglion Cells - drug effects; Retinal Ganglion Cells - pathology; Retinal nerve fiber layer; RFNL; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - pathology; Tomography, Optical Coherence; Neuroimaging; OCT; Retinal nerve fiber layer; Psychotic episode; Optical coherence tomography; RFNL; Schizophrenia

Optical coherence tomography (OCT) has been recently used to investigate neuropsychiatric disorders. We aimed to study retinal OCT measures of patients with schizophrenia with respect to healthy controls, and to evaluate possible differences between recent illness episode (RIE) and non-recent illnes...