miR‐126‐3p is essential for CXCL12‐induced angiogenesis

• Published in: Journal of cellular and molecular medicine Vol. 25; no. 13; pp. 6032 - 6045
• Main Authors: Bassand, Kévin, Metzinger, Laurent, Naïm, Meriem, Mouhoubi, Nesrine, Haddad, Oualid, Assoun, Vincent, Zaïdi, Naïma, Sainte‐Catherine, Odile, Butt, Amena, Guyot, Erwan, Oudar, Olivier, Laguillier‐Morizot, Christelle, Sutton, Angela, Charnaux, Nathalie, Metzinger‐Le Meuth, Valérie, Hlawaty, Hanna
• Format: Journal Article
• Language: English
• Published: England Wiley Open Access 01.07.2021; John Wiley and Sons Inc
• Subjects: Life Sciences; Original; endothelial cells; miR-126; chemokine CXCL12; angiogenesis

Atherosclerosis, in the ultimate stage of cardiovascular diseases, causes an obstruction of vessels leading to ischemia and finally to necrosis. To restore vascularization and tissue regeneration, stimulation of angiogenesis is necessary. Chemokines and microRNAs (miR) were studied as pro‐angiogenic...