Resistance of Field-Isolated Porcine Epidemic Diarrhea Virus to Interferon and Neutralizing Antibody

• Published in: Veterinary sciences Vol. 9; no. 12; p. 690
• Main Authors: Park, Jung-Eun, Shin, Hyun-Jin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.12.2022; MDPI
• Subjects: Alveoli; Antibiotics; Antibodies; Antigenicity; Biological response modifiers; Coronaviruses; Dehydration; Diarrhea; Disease resistance; Epidemics; Hogs; Infections; Infectivity; Interferon; Macrophages; Mortality; neutralizing antibody; Pathogenesis; Pathogenicity; Penicillin; porcine epidemic diarrhea virus; resistance; Suckling behavior; Transmissible gastroenteritis; Vaccines; Vero cells; Viral antibodies; Viral diseases; Viruses; Vomiting; South Korea; China; United States > US; Europe; neutralizing antibody; interferon; porcine epidemic diarrhea virus; resistance

Variant porcine epidemic diarrhea virus (PEDV), belonging to the genogroup G2b, has higher pathogenicity and mortality than classical PEDV, belonging to the genogroup G1a. To understand the pathogenesis of the G2b PEDV, we examined the resistance of the G2b PEDV to interferon (IFN) and neutralizing...