An iterative filtered backprojection inverse treatment planning algorithm for tomotherapy

• Published in: International journal of radiation oncology, biology, physics Vol. 32; no. 4; pp. 1215 - 1225
• Main Authors: Holmes, Timothy W., Mackie, T. Rock, Reckwerdt, Paul
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.07.1995; Elsevier
• Subjects: Algorithms; Biological and medical sciences; Breast Neoplasms - radiotherapy; Filtered backprojection; Humans; Image Processing, Computer-Assisted; Image reconstruction; Male; Medical sciences; Miscellaneous; Optimization; Prostatic Neoplasms - radiotherapy; Radiation therapy; Radiotherapy Planning, Computer-Assisted - methods; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Tomotherapy; Treatment planning; Filtered backprojection; Radiation therapy; Tomotherapy; Treatment planning; Optimization; Image reconstruction; Biomedical data processing; Instrumentation therapy; Tomography; Radiotherapy; Algorithm; Computer aid; Biomedical engineering; Inverse problem

An inverse treatment planning algorithm for tomotherapy is described. The algorithm iteratively computes a set of nonnegative beam intensity profiles that minimizes the least-square residual dose defined in the target and selected normal tissue regions of interest. At each iteration the residual dos...