The Therapeutic Potential of Exosomes in Soft Tissue Repair and Regeneration

• Published in: International journal of molecular sciences Vol. 23; no. 7; p. 3869
• Main Authors: Wan, Rou, Hussain, Arif, Behfar, Atta, Moran, Steven L, Zhao, Chunfeng
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 31.03.2022; MDPI
• Subjects: Axonogenesis; Bone marrow; Cell proliferation; Cytokines; Exosomes; Extracellular Vesicles; Healing; Injuries; Lipids; Metabolites; Microscopy; Muscles; Myogenesis; peripheral nerve healing; Peripheral nerves; Proteins; Quality of Life; Recovery of function; Regeneration (physiology); Regenerative Medicine; Repair; repair and regeneration; Review; Scars; Schwann Cells; Signal processing; Skeletal muscle; skeletal muscle healing; soft tissue healing; Soft tissues; Stem cells; tendon healing; Tendons; Tissue engineering; Trauma; Tumors; soft tissue healing; extracellular vesicles; exosomes; peripheral nerve healing; therapeutic applications; skeletal muscle healing; tendon healing; repair and regeneration

Soft tissue defects are common following trauma and tumor extirpation. These injuries can result in poor functional recovery and lead to a diminished quality of life. The healing of skin and muscle is a complex process that, at present, leads to incomplete recovery and scarring. Regenerative medicin...