Role of Omentin, Vaspin, Cardiotrophin-1, TWEAK and NOV/CCN3 in Obesity and Diabetes Development

• Published in: International journal of molecular sciences Vol. 18; no. 8; p. 1770
• Main Authors: Escoté, Xavier, Gómez-Zorita, Saioa, López-Yoldi, Miguel, Milton-Laskibar, Iñaki, Fernández-Quintela, Alfredo, Martínez, J., Moreno-Aliaga, María, Portillo, María
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15.08.2017; MDPI
• Subjects: Adipocytes; Animals; Cytokine TWEAK - genetics; Cytokine TWEAK - metabolism; Cytokines - genetics; Cytokines - metabolism; Diabetes; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - pathology; Gene expression; GPI-Linked Proteins - genetics; GPI-Linked Proteins - metabolism; Humans; Insulin; Lectins - genetics; Lectins - metabolism; Nephroblastoma Overexpressed Protein - genetics; Nephroblastoma Overexpressed Protein - metabolism; Obesity; Obesity - genetics; Obesity - metabolism; Obesity - pathology; Review; Serpins - genetics; Serpins - metabolism; cardiotrophin-1; adipokines; omentin; vaspin; TWEAK and NOV/CCN3

Adipose tissue releases bioactive mediators called adipokines. This review focuses on the effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of Apoptosis (TWEAK) and nephroblastoma overexpressed (NOV/CCN3) on obesity and diabetes. Omentin is produced by the stromal-...