Genomic paradigms for food-borne enteric pathogen analysis at the USFDA: case studies highlighting method utility, integration and resolution

• Published in: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment Vol. 30; no. 8; pp. 1422 - 1436
• Main Authors: Elkins, C.A, Kotewicz, M.L, Jackson, S.A, Lacher, D.W, Abu-Ali, G.S, Patel, I.R
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Abingdon Taylor & Francis 01.08.2013; Taylor & Francis Ltd
• Subjects: Animals; Bacteria; Biological and medical sciences; Biotechnology; case studies; Center for Food Safety and Applied Nutrition; chromosome mapping; Deoxyribonucleic acid; Disease Outbreaks; DNA; DNA, Bacterial - genetics; Escherichia coli; Food industries; food pathogens; Food safety; food-borne bacterial pathogens; Foodborne Diseases - epidemiology; Foodborne Diseases - microbiology; Fundamental and applied biological sciences. Psychology; genes; Genome, Bacterial; genomic methods; Genomics; Genomics - methods; Genotype; Genotype & phenotype; genotyping; Government agencies; Humans; microarray technology; monitoring; Oligonucleotide Array Sequence Analysis; Phylogeny; regulatory science; risk reduction; Salmonella enterica; Salmonella enterica - genetics; serotypes; Shiga toxin-producing Escherichia coli; Shiga-Toxigenic Escherichia coli - genetics; single nucleotide polymorphism; strain discrimination; United States - epidemiology; United States Food and Drug Administration; United States; United States > US; regulatory science; Genomics; Method; Strain; Case study; Regulation(control); Discrimination; Analysis; Pathogenic; genomic methods; strain discrimination; Bacteria; food-borne bacterial pathogens; Food

Modern risk control and food safety practices involving food-borne bacterial pathogens are benefiting from new genomic technologies for rapid, yet highly specific, strain characterisations. Within the United States Food and Drug Administration (USFDA) Center for Food Safety and Applied Nutrition (CF...