Patterns of Recurrence in Electively Irradiated Lymph Node Regions After Definitive Accelerated Intensity Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma

• Published in: International journal of radiation oncology, biology, physics Vol. 94; no. 4; pp. 766 - 774
• Main Authors: van den Bosch, Sven, MD, Dijkema, Tim, MD, PhD, Verhoef, Lia C.G., MD, PhD, Zwijnenburg, Ellen M., MD, Janssens, Geert O., MD, Kaanders, Johannes H.A.M., MD, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.03.2016
• Subjects: Aged; BIOMEDICAL RADIOGRAPHY; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - radiotherapy; COMPUTERIZED TOMOGRAPHY; Confidence Intervals; Female; GY RANGE 10-100; HEAD; Head and Neck Neoplasms - mortality; Head and Neck Neoplasms - pathology; Head and Neck Neoplasms - radiotherapy; Hematology, Oncology and Palliative Medicine; Humans; Hypopharyngeal Neoplasms - mortality; Hypopharyngeal Neoplasms - pathology; Hypopharyngeal Neoplasms - radiotherapy; IRRADIATION; Laryngeal Neoplasms - mortality; Laryngeal Neoplasms - pathology; Laryngeal Neoplasms - radiotherapy; LYMPH NODES; Lymph Nodes - pathology; Lymph Nodes - radiation effects; Lymphatic Irradiation; Male; Middle Aged; NECK; Neoplasm Recurrence, Local - mortality; NEOPLASMS; Oropharyngeal Neoplasms - mortality; Oropharyngeal Neoplasms - pathology; Oropharyngeal Neoplasms - radiotherapy; RADIATION DOSES; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; RADIOTHERAPY; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated - methods; RISK ASSESSMENT; Tumor Burden

Purpose To provide a comprehensive risk assessment on the patterns of recurrence in electively irradiated lymph node regions after definitive radiation therapy for head and neck cancer. Methods and Materials Two hundred sixty-four patients with stage cT2-4N0-2M0 squamous cell carcinoma of the oropha...