BioSeq-BLM: a platform for analyzing DNA, RNA and protein sequences based on biological language models

• Published in: Nucleic acids research Vol. 49; no. 22; p. e129
• Main Authors: Li, Hong-Liang, Pang, Yi-He, Liu, Bin
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 16.12.2021
• Subjects: Deoxyribonuclease I; DNA-Binding Proteins - chemistry; Intrinsically Disordered Proteins - chemistry; Methods Online; MicroRNAs - chemistry; Models, Statistical; Natural Language Processing; Nucleic Acid Conformation; RNA Precursors - chemistry; RNA-Binding Proteins - chemistry; Sequence Analysis, DNA - methods; Sequence Analysis, Protein - methods; Sequence Analysis, RNA - methods; Software

Abstract In order to uncover the meanings of ‘book of life’, 155 different biological language models (BLMs) for DNA, RNA and protein sequence analysis are discussed in this study, which are able to extract the linguistic properties of ‘book of life’. We also extend the BLMs into a system called Bio...