The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer’s Disease-Related Pathologies in APP/PS1 Transgenic Mice

• Published in: International journal of molecular sciences Vol. 19; no. 2; p. 598
• Main Authors: Tzeng, Tsai-Teng, Chen, Chien-Chih, Chen, Chin-Chu, Tsay, Huey-Jen, Lee, Li-Ya, Chen, Wan-Ping, Shen, Chien-Chang, Shiao, Young-Ji
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 17.02.2018; MDPI
• Subjects: Neurogenesis; Pathology; Rodents; Traditional Chinese medicine; Transgenic animals; erinacines; Alzheimer’s disease; neurogenesis; APPswe/PS1dE9 transgenic mice; amyloid plaque; astrocytes; microglia

Hericium erinaceus was used in traditional Chinese medicine for physiologically beneficial medicines. Recently, it has become a candidate in causing positive brain health-related activities. We previously reported that Hericium erinaceus mycelium ameliorates Alzheimer’s disease (AD)-related patholog...