Prevention of Gastric Cancer: Eradication of Helicobacter Pylori and Beyond

• Published in: International journal of molecular sciences Vol. 18; no. 8; p. 1699
• Main Authors: Tsukamoto, Tetsuya, Nakagawa, Mitsuru, Kiriyama, Yuka, Toyoda, Takeshi, Cao, Xueyuan
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.08.2017; MDPI
• Subjects: Animals; Bacteria; Gastric cancer; Helicobacter Infections - drug therapy; Helicobacter Infections - metabolism; Helicobacter Infections - microbiology; Helicobacter Infections - pathology; Helicobacter pylori; Humans; Public health; Review; Stomach Neoplasms - metabolism; Stomach Neoplasms - microbiology; Stomach Neoplasms - pathology; Stomach Neoplasms - prevention & control; chronic atrophic gastritis; chemoprevention; Helicobacter pylori; intestinal metaplasia; eradication

Although its prevalence is declining, gastric cancer remains a significant public health issue. The bacterium Helicobacter pylori is known to colonize the human stomach and induce chronic atrophic gastritis, intestinal metaplasia, and gastric cancer. Results using a Mongolian gerbil model revealed t...