Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human

• Published in: Molecular biology reports Vol. 34; no. 2; pp. 127 - 134
• Main Authors: Yu, Zhendong, Tang, Aifa, Gui, Yaoting, Guo, Xin, Zhu, Hui, Long, Yun, Li, Zeting, Cai, Zhiming
• Format: Journal Article
• Language: English
• Published: Netherlands Dordrecht : Kluwer Academic Publishers 01.06.2007; Springer Nature B.V
• Subjects: Affymetrix chip; Amino Acid Sequence; amino acid sequences; amino acids; Animals; Base Sequence; chemistry; Chlorocebus aethiops; Chromosomes; complementary DNA; COS Cells; Developmental stages; DNA, Complementary; DNA, Complementary - chemistry; Epididymis; essential genes; Female; Genes; genetics; Genomes; growth & development; Humans; Male; males; Medical research; metabolism; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Molecular weight; Nucleotide sequence; open reading frames; Proteins; Proteins - genetics; Proteins - metabolism; rats; reverse transcriptase polymerase chain reaction; RNA, Messenger; RNA, Messenger - metabolism; RNA-directed DNA polymerase; Sequence Alignment; Spermatogenesis; Testes; Testis; Testis - growth & development; Testis - metabolism; Testis-specific gene

Testis-specific genes are essential for spermatogenesis in mammalian male reproduction. We have identified a novel gene, Tsc21, exclusively expressed in mice and human testes from the results of the Affymetrix Genechip analysis in the six developmental stages of testis of postnatal Balb/C mice. The...