Ameliorating Effects of TRIM67 against Intestinal Inflammation and Barrier Dysfunction Induced by High Fat Diet in Obese Mice

• Published in: International journal of molecular sciences Vol. 23; no. 14; p. 7650
• Main Authors: Luo, Qihui, Jahangir, Asad, He, Junbo, Huang, Chao, Xia, Yu, Jia, Lanlan, Wei, Xiaoli, Pan, Ting, Du, Yanni, Mu, Bin, Gong, Huan, Liu, Wentao, Ur-Rehman, Saif, Pan, Kangcheng, Chen, Zhengli
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.07.2022; MDPI
• Subjects: Animals; Apoptosis; Autophagy; Carcinogenesis; Carcinogens; Colon; Cytokines; Cytoskeletal Proteins; Diet; Diet, High-Fat - adverse effects; High fat diet; Ileum; Immune response; In vivo methods and tests; Inflammation; Inflammation - pathology; Inflammatory bowel disease; Intestine; knockout; Metabolic disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Myc protein; Obesity; Obesity - metabolism; Oxidative stress; Palmitic acid; Permeability; Protein expression; Proteins; Small intestine; Swine; TRIM67; Tripartite Motif Proteins - metabolism; knockout; intestine; inflammation; high fat diet; TRIM67

Tripartite Motif 67 (TRIM67) is an important member of TRIM family proteins, which participates in different cellular processes including immune response, proliferation, differentiation, carcinogenesis, and apoptosis. In recent years, a high fat diet (HFD) has remained one of the main causes of diff...