Influence of Critical Parameters on Cytotoxicity Induced by Mesoporous Silica Nanoparticles

• Published in: Nanomaterials (Basel, Switzerland) Vol. 12; no. 12; p. 2016
• Main Authors: Ahmadi, Amirsadra, Sokunbi, Moses, Patel, Trisha, Chang, Ming-Wei, Ahmad, Zeeshan, Singh, Neenu
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.06.2022; MDPI
• Subjects: Bioavailability; Biocompatibility; Biomedical materials; Cell viability; Cytotoxicity; Diameters; functionalisation; Investigations; mesoporous silica nanoparticles; Morphology; Nanomaterials; Nanoparticles; nanotoxicology; Outliers (statistics); Parameters; Physicochemical properties; Pore size; Silica; Silicon dioxide; Statistical analysis; Surface charge; Surface chemistry; Surface stability; Thermal stability; Toxicity; Zeta potential; toxicity; mesoporous silica nanoparticles; diameter size; incubation; functionalisation; zeta potential; cytotoxicity; nanotoxicology

Mesoporous Silica Nanoparticles (MSNs) have received increasing attention in biomedical applications due to their tuneable pore size, surface area, size, surface chemistry, and thermal stability. The biocompatibility of MSNs, although generally believed to be satisfactory, is unclear. Physicochemica...