Increased brain gyrification in the schizophrenia spectrum
Aim Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes. Methods This magnetic resonance ima...
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| Published in | Psychiatry and clinical neurosciences Vol. 74; no. 1; pp. 70 - 76 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Melbourne
John Wiley & Sons Australia, Ltd
01.01.2020
Wiley Subscription Services, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1323-1316 1440-1819 1440-1819 |
| DOI | 10.1111/pcn.12939 |
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| Abstract | Aim
Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes.
Methods
This magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1‐weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups.
Results
Both schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups.
Conclusion
Increased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis. |
|---|---|
| AbstractList | Aim
Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes.
Methods
This magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1‐weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups.
Results
Both schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups.
Conclusion
Increased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis. Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes.AIMIncreased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes.This magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1-weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups.METHODSThis magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1-weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups.Both schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups.RESULTSBoth schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups.Increased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis.CONCLUSIONIncreased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis. AimIncreased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes.MethodsThis magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1‐weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups.ResultsBoth schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups.ConclusionIncreased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis. Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it remains unknown whether patients with schizotypal disorder exhibit similar changes. This magnetic resonance imaging study investigated brain gyrification in 46 patients with schizotypal disorder (29 male, 17 female), 101 patients with schizophrenia (55 male, 46 female), and 77 healthy controls (44 male, 33 female). T1-weighted magnetic resonance images were obtained for each participant. Using FreeSurfer software, the local gyrification index (LGI) of the entire cortex was compared across the groups. Both schizophrenia and schizotypal disorder patients showed a significantly higher LGI in diverse cortical regions, including the bilateral prefrontal and left parietal cortices, as compared with controls, but its extent was broader in schizophrenia especially for the right prefrontal and left occipital regions. No significant correlations were found between the LGI and clinical variables (e.g., symptom severity, medication) for either of the patient groups. Increased LGI in the frontoparietal regions was common to both patient groups and might represent vulnerability to schizophrenia, while more diverse changes in schizophrenia patients might be associated with the manifestation of florid psychosis. |
| Author | Kido, Mikio Nemoto, Kiyotaka Suzuki, Michio Nakamura, Mihoko Takayanagi, Yoichiro Noguchi, Kyo Sasabayashi, Daiki Nishikawa, Yumiko Furuichi, Atsushi Takahashi, Tsutomu |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31596011$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1007/s00429-011-0374-1 10.1038/385313a0 10.1111/pcn.12670 10.1176/appi.ajp.160.9.1606 10.1111/j.1600-0447.1999.tb05985.x 10.1016/S0920-9964(00)00131-6 10.1016/j.biopsych.2007.04.012 10.2174/1874440001307010015 10.1001/archpsyc.1992.01820080023004 10.3389/fnhum.2013.00750 10.1016/j.bpsc.2018.01.003 10.1016/j.neuroimage.2012.01.021 10.1002/hbm.23455 10.1176/appi.ajp.159.9.1521 10.1001/archpsyc.57.7.692 10.1016/j.jad.2015.06.014 10.1017/S0033291711002315 10.1093/brain/120.2.257 10.1016/j.biopsych.2004.04.007 10.1001/jamapsychiatry.2018.0391 10.1016/j.euroneuro.2009.07.007 10.1001/archpsyc.1990.01810190034005 10.1016/j.biopsych.2003.12.027 10.1016/j.biopsych.2005.04.016 10.1016/j.pnpbp.2014.02.005 10.1093/cercor/bhy111 10.1007/s10548-015-0468-9 10.1016/j.schres.2006.01.016 10.1016/j.schres.2007.12.472 10.1016/j.schres.2010.05.006 10.1016/j.schres.2006.08.004 10.1016/j.psychres.2007.08.011 10.1016/j.schres.2012.08.022 10.1016/S0893-133X(99)00096-2 10.1016/j.schres.2013.09.013 10.1038/nn804 10.1093/schbul/sbt050 10.1007/s00406-012-0343-6 10.1001/jamapsychiatry.2013.665 10.1016/j.schres.2010.08.033 10.1016/j.neuroimage.2011.12.058 10.1093/oso/9780195134759.001.0001 10.1016/j.pscychresns.2017.01.011 10.1097/YCO.0b013e32835d9e6a 10.1093/brain/awh554 10.1016/S0006-3223(96)00292-2 10.1093/brain/awm007 10.1016/j.biopsych.2010.12.012 10.1016/j.schres.2013.03.028 10.1093/cercor/5.1.56 10.1093/cercor/bhw098 10.1016/j.biopsych.2017.05.018 10.1146/annurev.clinpsy.032408.153502 10.1093/schbul/sbt030 10.1176/ajp.157.1.34 10.1017/S0033291710001054 10.1109/TMI.2007.903576 10.1016/j.neuroimage.2012.06.034 10.1016/S0006-3223(03)00789-3 10.1007/s00406-004-0522-1 10.1016/j.bbr.2015.03.018 10.1176/appi.ajp.161.3.398 10.1016/S0006-3223(99)00030-X 10.1017/S0033291718001228 10.1038/nrn2575 10.1016/j.schres.2006.08.032 10.1017/S0033291705004393 10.1176/ajp.146.10.1280 10.1093/schbul/15.4.559 10.1016/j.pscychresns.2016.03.005 10.1016/j.tins.2013.01.006 10.1007/s00406-015-0587-z 10.2174/138161212799316235 10.1016/j.schres.2013.11.032 10.1016/j.schres.2009.12.038 10.1016/j.schres.2006.01.002 |
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| Keywords | local gyrification index magnetic resonance imaging occipital cortex prefrontal cortex schizotypal disorder |
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| References | 2012; 60 2015; 185 2013; 26 2017; 82 1997; 41 2004; 161 2016; 266 1999; 45 2002; 159 2013; 70 2012; 18 2001; 48 2013; 7 2008; 101 2004; 254 2009; 10 1990; 47 1989; 146 2000 2010; 119 2000; 57 2017; 38 1997; 385 2008; 27 2007; 130 2009; 165 2003; 160 1984 2019; 29 1983 2013; 151 2018; 72 2008; 63 1992; 49 2011; 69 2009; 19 2014; 51 2018; 75 2012; 63 2005; 35 2012; 62 2012; 141 2019; 4 1990; 128 2000; 157 2017; 27 2002; 5 2000; 22 2015; 287 2010; 123 2010; 121 2008 1997 2013; 147 1994 1993 2013; 263 2014; 40 2014; 152 1995; 5 2004; 55 2013; 36 2006; 83 1980; 53 2013; 218 1997; 120 2004; 56 2005; 128 1999; 395 2019; 49 2011; 41 2017; 261 2009; 5 1989; 15 2016; 29 2016; 26 2007; 89 2012; 42 2016; 250 2005; 58 e_1_2_8_28_1 World Health Organization (e_1_2_8_2_1) 1993 e_1_2_8_24_1 Toru M (e_1_2_8_31_1) 2008 e_1_2_8_47_1 e_1_2_8_49_1 e_1_2_8_81_1 e_1_2_8_5_1 e_1_2_8_7_1 e_1_2_8_9_1 Mesulam MM (e_1_2_8_68_1) 2000 e_1_2_8_20_1 e_1_2_8_43_1 e_1_2_8_66_1 e_1_2_8_22_1 e_1_2_8_45_1 e_1_2_8_64_1 e_1_2_8_87_1 Tanaka F (e_1_2_8_37_1) 1993 e_1_2_8_62_1 e_1_2_8_85_1 e_1_2_8_41_1 e_1_2_8_60_1 e_1_2_8_83_1 e_1_2_8_17_1 e_1_2_8_19_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_59_1 e_1_2_8_15_1 e_1_2_8_38_1 e_1_2_8_57_1 e_1_2_8_70_1 e_1_2_8_32_1 e_1_2_8_55_1 e_1_2_8_78_1 e_1_2_8_11_1 e_1_2_8_53_1 e_1_2_8_76_1 e_1_2_8_51_1 e_1_2_8_74_1 e_1_2_8_30_1 e_1_2_8_72_1 Andreasen NC (e_1_2_8_35_1) 1984 e_1_2_8_29_1 First MB (e_1_2_8_33_1) 1997 e_1_2_8_25_1 e_1_2_8_27_1 e_1_2_8_48_1 e_1_2_8_69_1 Welker WI (e_1_2_8_10_1) 1990; 128 Goldman‐Rakic PS (e_1_2_8_46_1) 1980; 53 e_1_2_8_80_1 e_1_2_8_4_1 e_1_2_8_6_1 e_1_2_8_8_1 e_1_2_8_21_1 e_1_2_8_42_1 e_1_2_8_88_1 e_1_2_8_23_1 e_1_2_8_44_1 e_1_2_8_65_1 e_1_2_8_86_1 e_1_2_8_63_1 e_1_2_8_84_1 e_1_2_8_40_1 e_1_2_8_61_1 e_1_2_8_82_1 Fuster JM (e_1_2_8_67_1) 1997 e_1_2_8_18_1 e_1_2_8_39_1 e_1_2_8_14_1 e_1_2_8_16_1 e_1_2_8_58_1 e_1_2_8_79_1 American Psychiatric Association (e_1_2_8_3_1) 1994 e_1_2_8_56_1 e_1_2_8_77_1 e_1_2_8_12_1 e_1_2_8_54_1 e_1_2_8_75_1 e_1_2_8_52_1 e_1_2_8_73_1 Sasabayashi D (e_1_2_8_26_1) 2017; 27 Andreasen NC (e_1_2_8_34_1) 1983 e_1_2_8_50_1 e_1_2_8_71_1 |
| References_xml | – volume: 5 start-page: 249 year: 2009 end-page: 275 article-title: When doors of perception close: Bottom‐up models of disrupted cognition in schizophrenia publication-title: Annu. Rev. Clin. Psychol. – volume: 63 start-page: 611 year: 2012 end-page: 621 article-title: Consistency and interpretation of changes in millimeter‐scale cortical intrinsic curvature across three independent datasets in schizophrenia publication-title: NeuroImage – volume: 19 start-page: 835 year: 2009 end-page: 840 article-title: Brain structural changes associated with chronicity and antipsychotic treatment in schizophrenia publication-title: Eur. Neuropsychopharmacol. – volume: 141 start-page: 119 year: 2012 end-page: 127 article-title: Anterior limb of the internal capsule in schizotypal personality disorder: Fiber‐tract counting, volume, and anisotropy publication-title: Schizophr. Res. – volume: 55 start-page: 859 year: 2004 end-page: 867 article-title: Abnormal gyral complexity in first‐episode schizophrenia publication-title: Biol. Psychiatry – volume: 18 start-page: 434 year: 2012 end-page: 442 article-title: Relationship between gyrification and functional connectivity of the prefrontal cortex in subjects at high genetic risk of schizophrenia publication-title: Curr. Pharm. Des. – volume: 146 start-page: 1280 year: 1989 end-page: 1284 article-title: Risk of schizophrenia in character disordered patients publication-title: Am. J. Psychiatry – volume: 63 start-page: 80 year: 2008 end-page: 85 article-title: Increased right prefrontal cortical folding in adolescents at risk of schizophrenia for cognitive reasons publication-title: Biol. Psychiatry – volume: 27 start-page: 161 year: 2008 end-page: 170 article-title: A surface‐based approach to quantify local cortical gyrification publication-title: IEEE Trans. Med. Imaging – volume: 51 start-page: 166 year: 2014 end-page: 171 article-title: The polymorphism of YWHAE, a gene encoding 14‐3‐3epsilon, and orbitofrontal sulcogyral pattern in patients with schizophrenia and healthy subjects publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry – volume: 159 start-page: 1521 year: 2002 end-page: 1527 article-title: Smaller left Heschl's gyrus volume in patients with schizotypal personality disorder publication-title: Am. J. Psychiatry – volume: 47 start-page: 634 year: 1990 end-page: 640 article-title: Increased morbid risk for schizophrenia‐related disorders in relatives of schizotypal personality disordered patients publication-title: Arch. Gen. Psychiatry – volume: 83 start-page: 29 year: 2006 end-page: 40 article-title: Transition rates from schizotypal disorder to psychotic disorder for first‐contact patients included in the OPUS trial. A randomized clinical trial of integrated treatment and standard treatment publication-title: Schizophr. Res. – volume: 27 start-page: 2686 year: 2017 end-page: 2694 article-title: Increased frontal gyrification negatively correlates with executive function in patients with first‐episode schizophrenia publication-title: Cereb. Cortex – year: 1994 – volume: 49 start-page: 573 year: 2019 end-page: 580 article-title: Altered brain gyrification in deficit and non‐deficit schizophrenia publication-title: Psychol. Med. – volume: 29 start-page: 2412 year: 2019 end-page: 2423 article-title: Local cortical gyrification is increased in children with autism spectrum disorders, but decreases rapidly in adolescents publication-title: Cereb. Cortex – volume: 57 start-page: 692 year: 2000 end-page: 699 article-title: Planum temporale and Heschl gyrus volume reduction in schizophrenia: A magnetic resonance imaging study of first‐episode patients publication-title: Arch. Gen. Psychiatry – volume: 38 start-page: 1299 year: 2017 end-page: 1310 article-title: Local gyrification index in patients with major depressive disorder and its association with tryptophan hydroxylase‐2 (TPH2) polymorphism publication-title: Hum. Brain Mapp. – volume: 72 start-page: 556 year: 2018 end-page: 571 article-title: Brain morphologic changes in early stages of psychosis: Implications for clinical application and early intervention publication-title: Psychiatry Clin. Neurosci. – volume: 41 start-page: 487 year: 2011 end-page: 497 article-title: Pathways between early visual processing and functional outcome in schizophrenia publication-title: Psychol. Med. – volume: 287 start-page: 331 year: 2015 end-page: 339 article-title: Cortical gyrification and its relationships with cortical volume, cortical thickness, and cognitive performance in healthy mid‐life adults publication-title: Behav. Brain Res. – volume: 254 start-page: 406 year: 2004 end-page: 414 article-title: Structural brain differences in patients with schizophrenia and schizotypal disorder demonstrated by voxel‐based morphometry publication-title: Eur. Arch. Psychiatry Clin. Neurosci. – volume: 89 start-page: 49 year: 2007 end-page: 58 article-title: MRI abnormalities of the hippocampus and cavum septi pellucidi in females with schizotypal personality disorder publication-title: Schizophr. Res. – volume: 130 start-page: 693 year: 2007 end-page: 707 article-title: Altered orbitofrontal sulcogyral pattern in schizophrenia publication-title: Brain – volume: 395 start-page: 68 year: 1999 end-page: 79 article-title: Schizophrenia and the disconnection hypothesis publication-title: Acta Psychiatr. Scand. Suppl. – volume: 4 start-page: 434 year: 2019 end-page: 443 article-title: Cortical morphometry in the psychosis risk period: A comprehensive perspective of surface features publication-title: Biol. Psychiatry Cogn. Neurosci. Neuroimaging – volume: 123 start-page: 137 year: 2010 end-page: 144 article-title: Increased parahippocampal and lingual gyrification in first‐episode schizophrenia publication-title: Schizophr. Res. – volume: 60 start-page: 693 year: 2012 end-page: 699 article-title: Differential effects of surface area, gyrification and cortical thickness on voxel based morphometric deficits in schizophrenia publication-title: NeuroImage – volume: 56 start-page: 182 year: 2004 end-page: 189 article-title: Abnormal cortical folding in high‐risk individuals: A predictor of the development of schizophrenia? publication-title: Biol. Psychiatry – year: 2008 – volume: 147 start-page: 39 year: 2013 end-page: 45 article-title: Gyrification of Broca's region is anomalously lateralized at onset of schizophrenia in adolescence and regresses at 2 year follow‐up publication-title: Schizophr. Res. – volume: 152 start-page: 333 year: 2014 end-page: 338 article-title: Reduced brain cortical folding in schizophrenia revealed in two independent samples publication-title: Schizophr. Res. – year: 1997 – volume: 157 start-page: 34 year: 2000 end-page: 39 article-title: Disturbed gyrification of the prefrontal region in male schizophrenic patients: A morphometric postmortem study publication-title: Am. J. Psychiatry – volume: 41 start-page: 995 year: 1997 end-page: 999 article-title: Cortical abnormality in schizophrenia: An in vivo application of the gyrification index publication-title: Biol. Psychiatry – volume: 266 start-page: 15 year: 2016 end-page: 23 article-title: Orbitofrontal sulcogyral pattern and olfactory sulcus depth in the schizophrenia spectrum publication-title: Eur. Arch. Psychiatry Clin. Neurosci. – volume: 128 start-page: 2109 year: 2005 end-page: 2122 article-title: Differential contributions of prefrontal and temporolimbic pathology to mechanisms of psychosis publication-title: Brain – volume: 5 start-page: 56 year: 1995 end-page: 63 article-title: The ontogeny of human gyrification publication-title: Cereb. Cortex – volume: 70 start-page: 361 year: 2013 end-page: 372 article-title: Globally and locally reduced MRI gray matter volumes in neuroleptic‐naive men with schizotypal personality disorder: Association with negative symptoms publication-title: JAMA Psychiatry – volume: 218 start-page: 51 year: 2013 end-page: 58 article-title: The visual cortex in schizophrenia: Alterations of gyrification rather than cortical thickness–a combined cortical shape analysis publication-title: Brain Struct. Funct. – volume: 120 start-page: 257 year: 1997 end-page: 269 article-title: Genetic variability of human brain size and cortical gyral patterns publication-title: Brain – year: 1993 – volume: 40 start-page: 420 year: 2014 end-page: 427 article-title: Global association between cortical thinning and white matter integrity reduction in schizophrenia publication-title: Schizophr. Bull. – volume: 121 start-page: 55 year: 2010 end-page: 65 article-title: Volume reduction and altered sulco‐gyral pattern of the orbitofrontal cortex in first‐episode schizophrenia publication-title: Schizophr. Res. – volume: 82 start-page: 737 year: 2017 end-page: 745 article-title: Increased occipital gyrification and development of psychotic disorders in individuals with an at‐risk mental state: A multicenter study publication-title: Biol. Psychiatry – year: 1983 – volume: 49 start-page: 615 year: 1992 end-page: 623 article-title: The Comprehensive Assessment of Symptoms and History (CASH). An instrument for assessing diagnosis and psychopathology publication-title: Arch. Gen. Psychiatry – volume: 45 start-page: 1393 year: 1999 end-page: 1402 article-title: Schizotypal personality disorder and MRI abnormalities of temporal lobe gray matter publication-title: Biol. Psychiatry – volume: 29 start-page: 382 year: 2016 end-page: 394 article-title: Neuroanatomical markers of neurological soft signs in recent‐onset schizophrenia and Asperger‐syndrome publication-title: Brain Topogr. – volume: 7 start-page: 15 year: 2013 end-page: 26 article-title: Dysfunctional cortical connectivity during the auditory oddball task in patients with schizophrenia publication-title: Open Neuroimag. J. – volume: 119 start-page: 232 year: 2010 end-page: 239 article-title: Reduced white matter integrity as a neural correlate of social cognition deficits in schizophrenia publication-title: Schizophr. Res. – volume: 185 start-page: 104 year: 2015 end-page: 107 article-title: Prefrontal gyrification in psychotic bipolar I disorder vs. schizophrenia publication-title: J. Affect. Disord. – volume: 22 start-page: 125 year: 2000 end-page: 132 article-title: The relationship between dorsolateral prefrontal neuronal N‐acetylaspartate and evoked release of striatal dopamine in schizophrenia publication-title: Neuropsychopharmacology – volume: 89 start-page: 35 year: 2007 end-page: 48 article-title: Parietal lobe volume deficits in schizophrenia spectrum disorders publication-title: Schizophr. Res. – volume: 75 start-page: 613 year: 2018 end-page: 622 article-title: Disorganized gyrification network properties during the transition to psychosis publication-title: JAMA Psychiatry – volume: 35 start-page: 1019 year: 2005 end-page: 1030 article-title: Functional MRI of visuospatial working memory in schizotypal personality disorder: A region‐of‐interest analysis publication-title: Psychol. Med. – volume: 26 start-page: 3297 year: 2016 end-page: 3309 article-title: Relationship between cortical gyrification, white matter connectivity, and autism spectrum disorder publication-title: Cereb. Cortex – volume: 385 start-page: 313 year: 1997 end-page: 318 article-title: A tension‐based theory of morphogenesis and compact wiring in the central nervous system publication-title: Nature – volume: 40 start-page: 675 year: 2014 end-page: 684 article-title: Diagnostic discontinuity in psychosis: A combined study of cortical gyrification and functional connectivity publication-title: Schizophr. Bull. – volume: 53 start-page: 1 year: 1980 end-page: 19 article-title: Morphological consequences of prenatal injury to the primate brain publication-title: Prog. Brain Res. – volume: 55 start-page: 141 year: 2004 end-page: 147 article-title: Gyrification in first‐episode schizophrenia: A morphometric study publication-title: Biol. Psychiatry – volume: 69 start-page: 974 year: 2011 end-page: 979 article-title: Folding of the prefrontal cortex in schizophrenia: Regional differences in gyrification publication-title: Biol. Psychiatry – volume: 62 start-page: 774 year: 2012 end-page: 781 article-title: FreeSurfer publication-title: NeuroImage – volume: 7 start-page: 750 year: 2013 article-title: Decreased frontal gyrification correlates with altered connectivity in children with autism publication-title: Front. Hum. Neurosci. – volume: 261 start-page: 91 year: 2017 end-page: 95 article-title: Increased white matter radial diffusivity is associated with prefrontal cortical folding deficits in schizophrenia publication-title: Psychiatry Res. Neuroimaging – volume: 36 start-page: 275 year: 2013 end-page: 284 article-title: Development of cortical folding during evolution and ontogeny publication-title: Trends Neurosci. – volume: 161 start-page: 398 year: 2004 end-page: 413 article-title: The pathophysiology of schizophrenia disorders: Perspectives from the spectrum publication-title: Am. J. Psychiatry – volume: 10 start-page: 186 year: 2009 end-page: 198 article-title: Complex brain networks: Graph theoretical analysis of structural and functional systems publication-title: Nat. Rev. Neurosci. – year: 1984 – volume: 5 start-page: 267 year: 2002 end-page: 271 article-title: Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia publication-title: Nat. Neurosci. – volume: 42 start-page: 1329 year: 2012 end-page: 1337 article-title: Cortical folding in Broca's area relates to obstetric complications in schizophrenia patients and healthy controls publication-title: Psychol. Med. – volume: 58 start-page: 468 year: 2005 end-page: 478 article-title: Fronto‐temporal disconnectivity in schizotypal personality disorder: A diffusion tensor imaging study publication-title: Biol. Psychiatry – volume: 101 start-page: 111 year: 2008 end-page: 123 article-title: Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients publication-title: Schizophr. Res. – volume: 165 start-page: 1 year: 2009 end-page: 9 article-title: Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: Preliminary evidence publication-title: Psychiatry Res. – volume: 128 start-page: 87 year: 1990 end-page: 109 article-title: The significance of foliation and fissuration of cerebellar cortex. The cerebellar folium as a fundamental unit of sensorimotor integration publication-title: Arch. Ital. Biol. – volume: 26 start-page: 172 year: 2013 end-page: 187 article-title: Review of functional and anatomical brain connectivity findings in schizophrenia publication-title: Curr. Opin. Psychiatry – volume: 83 start-page: 131 year: 2006 end-page: 143 article-title: Morphologic alterations of the parcellated superior temporal gyrus in schizophrenia spectrum publication-title: Schizophr. Res. – volume: 15 start-page: 559 year: 1989 end-page: 571 article-title: The Structured Interview for Schizotypy (SIS): A preliminary report publication-title: Schizophr. Bull. – volume: 250 start-page: 29 year: 2016 end-page: 32 article-title: Decreased number of orbital sulci in schizophrenia spectrum disorders publication-title: Psychiatry Res. Neuroimaging – volume: 151 start-page: 113 year: 2013 end-page: 123 article-title: Working memory in schizotypal personality disorder: fMRI activation and deactivation differences publication-title: Schizophr. Res. – volume: 160 start-page: 1606 year: 2003 end-page: 1613 article-title: Reduced cortical folding in schizophrenia: An MRI morphometric study publication-title: Am. J. Psychiatry – start-page: 1 year: 2000 end-page: 120 – volume: 263 start-page: 15 year: 2013 end-page: 24 article-title: Morphometry of structural disconnectivity indicators in subjects at risk and in age‐matched patients with schizophrenia publication-title: Eur. Arch. Psychiatry Clin. Neurosci. – volume: 48 start-page: 187 year: 2001 end-page: 199 article-title: Temporal lobe volume determined by magnetic resonance imaging in schizotypal personality disorder and schizophrenia publication-title: Schizophr. Res. – ident: e_1_2_8_18_1 doi: 10.1007/s00429-011-0374-1 – ident: e_1_2_8_11_1 doi: 10.1038/385313a0 – ident: e_1_2_8_7_1 doi: 10.1111/pcn.12670 – ident: e_1_2_8_15_1 doi: 10.1176/appi.ajp.160.9.1606 – ident: e_1_2_8_48_1 doi: 10.1111/j.1600-0447.1999.tb05985.x – ident: e_1_2_8_60_1 doi: 10.1016/S0920-9964(00)00131-6 – ident: e_1_2_8_27_1 doi: 10.1016/j.biopsych.2007.04.012 – ident: e_1_2_8_69_1 doi: 10.2174/1874440001307010015 – ident: e_1_2_8_32_1 doi: 10.1001/archpsyc.1992.01820080023004 – ident: e_1_2_8_43_1 doi: 10.3389/fnhum.2013.00750 – ident: e_1_2_8_83_1 doi: 10.1016/j.bpsc.2018.01.003 – volume-title: Structured Clinical Interview for DSM‐IV Axis II Personality Disorders year: 1997 ident: e_1_2_8_33_1 – ident: e_1_2_8_39_1 doi: 10.1016/j.neuroimage.2012.01.021 – ident: e_1_2_8_86_1 doi: 10.1002/hbm.23455 – ident: e_1_2_8_58_1 doi: 10.1176/appi.ajp.159.9.1521 – volume-title: MMPI Manual of New Japanese Version year: 1993 ident: e_1_2_8_37_1 – ident: e_1_2_8_36_1 doi: 10.1001/archpsyc.57.7.692 – ident: e_1_2_8_85_1 doi: 10.1016/j.jad.2015.06.014 – ident: e_1_2_8_16_1 doi: 10.1017/S0033291711002315 – ident: e_1_2_8_80_1 doi: 10.1093/brain/120.2.257 – volume: 27 start-page: 2686 year: 2017 ident: e_1_2_8_26_1 article-title: Increased frontal gyrification negatively correlates with executive function in patients with first‐episode schizophrenia publication-title: Cereb. Cortex – ident: e_1_2_8_73_1 doi: 10.1016/j.biopsych.2004.04.007 – ident: e_1_2_8_76_1 doi: 10.1001/jamapsychiatry.2018.0391 – ident: e_1_2_8_77_1 doi: 10.1016/j.euroneuro.2009.07.007 – volume: 128 start-page: 87 year: 1990 ident: e_1_2_8_10_1 article-title: The significance of foliation and fissuration of cerebellar cortex. The cerebellar folium as a fundamental unit of sensorimotor integration publication-title: Arch. Ital. Biol. – ident: e_1_2_8_4_1 doi: 10.1001/archpsyc.1990.01810190034005 – ident: e_1_2_8_23_1 doi: 10.1016/j.biopsych.2003.12.027 – ident: e_1_2_8_53_1 doi: 10.1016/j.biopsych.2005.04.016 – ident: e_1_2_8_82_1 doi: 10.1016/j.pnpbp.2014.02.005 – ident: e_1_2_8_87_1 doi: 10.1093/cercor/bhy111 – volume-title: The Prefrontal Cortex: Anatomy, Physiology, and Neuropsychology of the Frontal Lobe year: 1997 ident: e_1_2_8_67_1 – ident: e_1_2_8_88_1 doi: 10.1007/s10548-015-0468-9 – ident: e_1_2_8_62_1 doi: 10.1016/j.schres.2006.01.016 – volume-title: Scale for the Assessment of Positive Symptoms (SAPS) year: 1984 ident: e_1_2_8_35_1 – volume-title: Diagnostic and Statistical Manual of Mental Disorders year: 1994 ident: e_1_2_8_3_1 – ident: e_1_2_8_63_1 doi: 10.1016/j.schres.2007.12.472 – ident: e_1_2_8_41_1 doi: 10.1016/j.schres.2010.05.006 – ident: e_1_2_8_59_1 doi: 10.1016/j.schres.2006.08.004 – ident: e_1_2_8_81_1 doi: 10.1016/j.psychres.2007.08.011 – volume-title: Psychotropic Manual year: 2008 ident: e_1_2_8_31_1 – ident: e_1_2_8_54_1 doi: 10.1016/j.schres.2012.08.022 – ident: e_1_2_8_65_1 doi: 10.1016/S0893-133X(99)00096-2 – ident: e_1_2_8_56_1 doi: 10.1016/j.schres.2013.09.013 – ident: e_1_2_8_66_1 doi: 10.1038/nn804 – ident: e_1_2_8_19_1 doi: 10.1093/schbul/sbt050 – ident: e_1_2_8_25_1 doi: 10.1007/s00406-012-0343-6 – ident: e_1_2_8_52_1 doi: 10.1001/jamapsychiatry.2013.665 – ident: e_1_2_8_24_1 doi: 10.1016/j.schres.2010.08.033 – ident: e_1_2_8_64_1 doi: 10.1016/j.neuroimage.2011.12.058 – start-page: 1 volume-title: Principles of Behavioral and Cognitive Neurology year: 2000 ident: e_1_2_8_68_1 doi: 10.1093/oso/9780195134759.001.0001 – ident: e_1_2_8_45_1 doi: 10.1016/j.pscychresns.2017.01.011 – ident: e_1_2_8_49_1 doi: 10.1097/YCO.0b013e32835d9e6a – ident: e_1_2_8_50_1 doi: 10.1093/brain/awh554 – ident: e_1_2_8_13_1 doi: 10.1016/S0006-3223(96)00292-2 – ident: e_1_2_8_40_1 doi: 10.1093/brain/awm007 – ident: e_1_2_8_78_1 doi: 10.1016/j.biopsych.2010.12.012 – ident: e_1_2_8_79_1 doi: 10.1016/j.schres.2013.03.028 – ident: e_1_2_8_8_1 doi: 10.1093/cercor/5.1.56 – volume-title: Scale for the Assessment of Negative Symptoms (SANS) year: 1983 ident: e_1_2_8_34_1 – ident: e_1_2_8_44_1 doi: 10.1093/cercor/bhw098 – ident: e_1_2_8_74_1 doi: 10.1016/j.biopsych.2017.05.018 – ident: e_1_2_8_70_1 doi: 10.1146/annurev.clinpsy.032408.153502 – ident: e_1_2_8_47_1 doi: 10.1093/schbul/sbt030 – ident: e_1_2_8_14_1 doi: 10.1176/ajp.157.1.34 – ident: e_1_2_8_72_1 doi: 10.1017/S0033291710001054 – ident: e_1_2_8_29_1 doi: 10.1109/TMI.2007.903576 – ident: e_1_2_8_17_1 doi: 10.1016/j.neuroimage.2012.06.034 – ident: e_1_2_8_22_1 doi: 10.1016/S0006-3223(03)00789-3 – ident: e_1_2_8_61_1 doi: 10.1007/s00406-004-0522-1 – ident: e_1_2_8_84_1 doi: 10.1016/j.bbr.2015.03.018 – ident: e_1_2_8_30_1 doi: 10.1176/appi.ajp.161.3.398 – volume: 53 start-page: 1 year: 1980 ident: e_1_2_8_46_1 article-title: Morphological consequences of prenatal injury to the primate brain publication-title: Prog. Brain Res. – ident: e_1_2_8_57_1 doi: 10.1016/S0006-3223(99)00030-X – ident: e_1_2_8_21_1 doi: 10.1017/S0033291718001228 – ident: e_1_2_8_75_1 doi: 10.1038/nrn2575 – volume-title: The ICD‐10 Classification of Mental and Behavioral Disorders: Diagnostic Criteria for Research year: 1993 ident: e_1_2_8_2_1 – ident: e_1_2_8_51_1 doi: 10.1016/j.schres.2006.08.032 – ident: e_1_2_8_55_1 doi: 10.1017/S0033291705004393 – ident: e_1_2_8_5_1 doi: 10.1176/ajp.146.10.1280 – ident: e_1_2_8_28_1 doi: 10.1093/schbul/15.4.559 – ident: e_1_2_8_38_1 doi: 10.1016/j.pscychresns.2016.03.005 – ident: e_1_2_8_9_1 doi: 10.1016/j.tins.2013.01.006 – ident: e_1_2_8_42_1 doi: 10.1007/s00406-015-0587-z – ident: e_1_2_8_12_1 doi: 10.2174/138161212799316235 – ident: e_1_2_8_20_1 doi: 10.1016/j.schres.2013.11.032 – ident: e_1_2_8_71_1 doi: 10.1016/j.schres.2009.12.038 – ident: e_1_2_8_6_1 doi: 10.1016/j.schres.2006.01.002 |
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| Snippet | Aim
Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early... Increased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early... AimIncreased brain gyrification in diverse cortical regions has been reported in patients with schizophrenia, possibly reflecting deviations in early... |
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| StartPage | 70 |
| SubjectTerms | Cortex (parietal) local gyrification index Magnetic resonance imaging Mental disorders Neuroimaging occipital cortex Patients Prefrontal cortex Psychosis Schizophrenia schizotypal disorder |
| Title | Increased brain gyrification in the schizophrenia spectrum |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fpcn.12939 https://www.ncbi.nlm.nih.gov/pubmed/31596011 https://www.proquest.com/docview/2331689000 https://www.proquest.com/docview/2303200404 |
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