EFFECTS OF SOME S‐ALKYLTHIOURONIUMS AND RELATED COMPOUNDS ON THE OSMOTIC FRAGILITY AND THE MEMBRANE EXPANSION OF HUMAN ERYTHROCYTES

• Published in: British journal of pharmacology Vol. 71; no. 1; pp. 253 - 258
• Main Authors: BERESFORD, ROSEMARY A., FASTIER, F.N.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.1980; Nature Publishing Group
• Subjects: Chlorpromazine - pharmacology; Erythrocyte Membrane - drug effects; Erythrocytes - drug effects; Hemolysis - drug effects; Humans; In Vitro Techniques; Osmotic Fragility - drug effects; Procaine - pharmacology; Thiourea - pharmacology

1 Changes in the osmotic fragility and critical haemolytic volume of human erythrocytes produced by S‐n‐decylthiouronium (S‐10) and related compounds have been studied. 2 S‐10 had a biphasic action on osmotic fragility, protecting erythrocytes against lysis in low concentrations but producing lysis...