Zonulin transgenic mice show altered gut permeability and increased morbidity/mortality in the DSS colitis model - Sturgeon, Craig; Lan, Jinggang; Fasano, Alessio (Annals of the New York Academy of Sciences, 2017)
Keywords: Animals; barrier function; Body Weight - drug effects; Cholera Toxin - antagonists & inhibitors; Cholera Toxin - genetics; Cholera Toxin - metabolism; Colitis; Colitis - chemically induced; Colitis - genetics; Colitis - physiopathology; Dextran; Dextran Sulfate; Drinking water; Duodenum; Environmental monitoring; Female; Gene expression; Histology; Impairment; inflammation; Inflammatory bowel disease; Inflammatory diseases; Intestinal Mucosa - metabolism; Intestinal Mucosa - physiopathology; intestinal permeability; Intestine; Intestine, Small - metabolism; Intestine, Small - physiopathology; Jejunum; Kaplan-Meier Estimate; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morbidity; Mortality; Oligopeptides - pharmacology; Pathogenesis; Permeability; Permeability - drug effects; Rodents; Sodium; Sodium sulfate; Sulfates; Tight junctions; Time Factors; Transgenic mice; Weight loss; zonulin; intestinal permeability; zonulin; tight junctions; inflammation; barrier function