ACE2 expression in saliva of patients with COVID-19 and its association with Candida albicans and Aggregatibacter actinomycetemcomitans [version 2; peer review: 2 approved]

• Published in: F1000 research Vol. 11; p. 557
• Main Authors: Bachtiar, Endang W, Bachtiar, Boy M, Kusumaningrum, Ardiana, Sunarto, Hari, Soeroso, Yuniarti, Sulijaya, Benso, Apriyanti, Efa, Theodorea, Citra Fragrantia, Pratomo, Irandi Putra, ., Yudhistira, Efendi, Defi, Razak, Fathilah Abdul
• Format: Journal Article
• Language: English
• Published: England Faculty of 1000 Ltd 2022; F1000 Research Limited; F1000 Research Ltd
• Subjects: ACE2; Actin; Actins; Agglutinins - metabolism; Aggregatibacter actinomycetemcomitans; Angiotensin; Angiotensin-Converting Enzyme 2; Bacteria; Biofilms; Candida albicans; Coronaviruses; COVID-19; Diabetes; Diabetes mellitus; Dysbacteriosis; Dysbiosis; eng; Fusobacterium nucleatum; Gene expression; Genes; Gram-negative bacteria; Humans; Laboratories; Microbiota; Microorganisms; Patients; Peptidyl-dipeptidase A; RNA, Messenger - metabolism; Saliva; Saliva - microbiology; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Tongue; Veillonella parvula; United States > US; Taiwan; Indonesia; COVID-19; Candida albicans; ACE2; Aggregatibacter actinomycetemcomitans; Fusobacterium nucleatum; Veillonella parvula

Background: A relationship between oral microbiota and susceptibility to SARS-CoV-2 infection has been extensively studied. However, the relationship between oral commensal flora and expression of angiotensin-converting enzyme 2 ( ACE2) remains to be established. In this observational study, we coll...