ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer - Tang, Zhe; Pilié, Patrick G.; Geng, Chuandong; Manyam, Ganiraju C.; Yang, Guang; Park, Sanghee; Wang, Daoqi; Peng, Shan; Wu, Cheng; Peng, Guang; Yap, Timothy A.; Corn, Paul G.; et al. (Clinical cancer research, 2021)
Keywords: Animals; Ataxia Telangiectasia Mutated Proteins - antagonists & inhibitors; CDC2 Protein Kinase - physiology; Immune Checkpoint Inhibitors - therapeutic use; Male; Mice; Phthalazines - therapeutic use; Piperazines - therapeutic use; Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use; Prostatic Neoplasms - drug therapy; Repressor Proteins - physiology; Signal Transduction; Ubiquitin-Protein Ligase Complexes - physiology