Monacolin K affects lipid metabolism through SIRT1/AMPK pathway in HepG2 cells - Huang, Chia-Hsin; Shiu, Shin-Mau; Wu, Min-Tze; Chen, Wei-Lu; Wang, Shyang-Guang; Lee, Horng-Mo (Archives of pharmacal research, 2013)
Keywords: acetyl-CoA carboxylase; AMP-activated protein kinase; AMP-Activated Protein Kinases - metabolism; Anticholesteremic Agents - pharmacology; Cell Survival - drug effects; Cell Survival - physiology; cholesterol; Dose-Response Relationship, Drug; fatty-acid synthase; Hep G2 Cells; human cell lines; Humans; lipid content; lipid metabolism; Lipid Metabolism - drug effects; Lipid Metabolism - physiology; lovastatin; Lovastatin - pharmacology; Medicine; Monascus; nicotinamide; Pharmacology/Toxicology; Pharmacy; phosphorylation; protein synthesis; Research Article; secondary metabolites; Signal Transduction - drug effects; Signal Transduction - physiology; Sirtuin 1 - metabolism; triacylglycerol lipase; Western blotting; 약학; AMPK; Monacolin K; Statin; SIRT1; Lipid; FoxO1