Recent Developments in Automated Reactors for Plasmonic Nanoparticles

Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adapt...

Full description

Saved in:
Bibliographic Details
Published inNanomaterials (Basel, Switzerland) Vol. 15; no. 8; p. 607
Main Authors He, Shan, Luo, Tong, Chen, Xiao’e, Young, David James, Jellicoe, Matt
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 15.04.2025
MDPI
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adaptive manufacturing. Despite progress, challenges remain in integrating automation for complex, multistep syntheses due to the intricate interplay of chemical and physical processes. Emerging process analytical technologies and advanced control software are enhancing real-time monitoring, adaptive feedback loops, and self-optimizing synthesis strategies. We categorize these developments, emphasizing their impact on plasmonic nanomaterial fabrication and outlining future directions for autonomous synthesis.
AbstractList Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adaptive manufacturing. Despite progress, challenges remain in integrating automation for complex, multistep syntheses due to the intricate interplay of chemical and physical processes. Emerging process analytical technologies and advanced control software are enhancing real-time monitoring, adaptive feedback loops, and self-optimizing synthesis strategies. We categorize these developments, emphasizing their impact on plasmonic nanomaterial fabrication and outlining future directions for autonomous synthesis.
Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adaptive manufacturing. Despite progress, challenges remain in integrating automation for complex, multistep syntheses due to the intricate interplay of chemical and physical processes. Emerging process analytical technologies and advanced control software are enhancing real-time monitoring, adaptive feedback loops, and self-optimizing synthesis strategies. We categorize these developments, emphasizing their impact on plasmonic nanomaterial fabrication and outlining future directions for autonomous synthesis.Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adaptive manufacturing. Despite progress, challenges remain in integrating automation for complex, multistep syntheses due to the intricate interplay of chemical and physical processes. Emerging process analytical technologies and advanced control software are enhancing real-time monitoring, adaptive feedback loops, and self-optimizing synthesis strategies. We categorize these developments, emphasizing their impact on plasmonic nanomaterial fabrication and outlining future directions for autonomous synthesis.
Audience Academic
Author Luo, Tong
He, Shan
Chen, Xiao’e
Jellicoe, Matt
Young, David James
AuthorAffiliation 3 College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
2 James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK; david.j.young@glasgow.ac.uk
1 School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
AuthorAffiliation_xml – name: 1 School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
– name: 2 James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK; david.j.young@glasgow.ac.uk
– name: 3 College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia
Author_xml – sequence: 1
  givenname: Shan
  surname: He
  fullname: He, Shan
– sequence: 2
  givenname: Tong
  surname: Luo
  fullname: Luo, Tong
– sequence: 3
  givenname: Xiao’e
  surname: Chen
  fullname: Chen, Xiao’e
– sequence: 4
  givenname: David James
  surname: Young
  fullname: Young, David James
– sequence: 5
  givenname: Matt
  orcidid: 0000-0002-9079-5307
  surname: Jellicoe
  fullname: Jellicoe, Matt
BackLink https://www.ncbi.nlm.nih.gov/pubmed/40278472$$D View this record in MEDLINE/PubMed
BookMark eNpdUktv1DAQtlARLUtvnFEkLhzY4mfsnNCqFKhUAargbDn2ePEqsRc7qcS_xyVLtcVzmNH4m2-ez9FJTBEQeknwBWMdfhdNTERghVssn6AzimW35l1HTo7sU3Reyg7X1xGmBHuGTjmmUnFJz9DVLViIU_MB7mBI-7HapQmx2cxTGs0ErrkFY6eUS-NTbr4NpowpBtt8qZn3Jk_BDlBeoKfeDAXOD3qFfny8-n75eX3z9dP15eZmbbmU09oS3gNhwDy0LVhnWM-E9EJaTqWnsndSmk5QAkTVhnyvMGaUVG2VkcSyFbpeeF0yO73PYTT5t04m6L-OlLf6UJJ2TEnXs8rCWs656G1N5Ijy2IGwnatc7xeu_dyP4O6nkM3wiPTxTww_9TbdaUIx7VosKsObA0NOv2Yokx5DsTAMJkKai2ak461oVR37Cr3-D7pLc451VguK8U7IirpYUFtTOwjRp5rYVnEwBls370P1bxSTUtEaUgNeHffwUPy__VbA2wVgcyolg3-AEKzvL0gfXxD7A-Bat-o
Cites_doi 10.1038/s41524-021-00520-w
10.1039/D4RE00339J
10.1021/acsanm.2c02579
10.1007/s41981-020-00084-8
10.1039/D1SC05829K
10.1039/D3NA01080E
10.1039/C6CS00830E
10.3390/molecules28186624
10.1016/j.cis.2024.103263
10.1038/s41467-025-56788-9
10.1002/sstr.202300397
10.1038/s41598-022-09774-w
10.1038/s41573-020-0090-8
10.1002/adfm.202106725
10.1039/D4NR02516D
10.1126/sciadv.abo2626
10.1002/aenm.202100918
10.1021/acs.nanolett.4c05072
10.1002/cmtd.202300021
10.1002/smll.202106580
10.1002/chem.201700888
10.1016/j.chemosphere.2022.134427
10.1007/s10898-021-01052-9
10.1038/s41598-020-58580-9
10.2139/ssrn.5044345
10.1002/adfm.202312561
10.1126/science.aaf1337
10.26434/chemrxiv-2025-tx4tq
10.1039/D1RE00549A
10.1039/D1NA00195G
10.1038/s41467-020-16501-4
10.1098/rsos.191204
10.1039/D1CC00859E
10.2174/1568026616666160715163346
10.1021/acsnano.1c10919
10.1002/smll.202403529
10.1002/ange.202214511
10.1039/D4NH00174E
10.1021/acs.chemrev.2c00798
10.1016/j.cej.2018.07.031
ContentType Journal Article
Copyright COPYRIGHT 2025 MDPI AG
2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2025 by the authors. 2025
Copyright_xml – notice: COPYRIGHT 2025 MDPI AG
– notice: 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2025 by the authors. 2025
DBID AAYXX
CITATION
NPM
7QF
7QO
7QQ
7SC
7SE
7SP
7SR
7TA
7TB
7U5
8BQ
8FD
8FE
8FG
8FH
ABJCF
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
CCPQU
D1I
DWQXO
F28
FR3
GNUQQ
H8D
H8G
HCIFZ
JG9
JQ2
KB.
KR7
L7M
LK8
L~C
L~D
M7P
P64
PDBOC
PHGZM
PHGZT
PIMPY
PKEHL
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
7X8
5PM
DOA
DOI 10.3390/nano15080607
DatabaseName CrossRef
PubMed
Aluminium Industry Abstracts
Biotechnology Research Abstracts
Ceramic Abstracts
Computer and Information Systems Abstracts
Corrosion Abstracts
Electronics & Communications Abstracts
Engineered Materials Abstracts
Materials Business File
Mechanical & Transportation Engineering Abstracts
Solid State and Superconductivity Abstracts
METADEX
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
Materials Science & Engineering Collection
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Technology Collection
Natural Science Collection
ProQuest One
ProQuest Materials Science Collection
ProQuest Central
ANTE: Abstracts in New Technology & Engineering
Engineering Research Database
ProQuest Central Student
Aerospace Database
Copper Technical Reference Library
SciTech Premium Collection
Materials Research Database
ProQuest Computer Science Collection
Materials Science Database
Civil Engineering Abstracts
Advanced Technologies Database with Aerospace
Biological Sciences
Computer and Information Systems Abstracts – Academic
Computer and Information Systems Abstracts Professional
Biological Science Database
Biotechnology and BioEngineering Abstracts
Materials Science Collection
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Open Access Full Text
DatabaseTitle CrossRef
PubMed
Publicly Available Content Database
Materials Research Database
ProQuest Central Student
ProQuest Central Essentials
ProQuest Computer Science Collection
Computer and Information Systems Abstracts
SciTech Premium Collection
ProQuest Central China
Materials Business File
ProQuest One Applied & Life Sciences
Engineered Materials Abstracts
Natural Science Collection
Biological Science Collection
ProQuest Central (New)
ANTE: Abstracts in New Technology & Engineering
Aluminium Industry Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
Electronics & Communications Abstracts
ProQuest Technology Collection
Ceramic Abstracts
Biological Science Database
Biotechnology and BioEngineering Abstracts
ProQuest One Academic UKI Edition
Solid State and Superconductivity Abstracts
Engineering Research Database
ProQuest One Academic
ProQuest One Academic (New)
Technology Collection
Technology Research Database
Computer and Information Systems Abstracts – Academic
ProQuest One Academic Middle East (New)
Mechanical & Transportation Engineering Abstracts
Materials Science Collection
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Central
Aerospace Database
Copper Technical Reference Library
Biotechnology Research Abstracts
ProQuest Central Korea
Materials Science Database
Advanced Technologies Database with Aerospace
ProQuest Materials Science Collection
Civil Engineering Abstracts
ProQuest SciTech Collection
METADEX
Computer and Information Systems Abstracts Professional
Materials Science & Engineering Collection
Corrosion Abstracts
MEDLINE - Academic
DatabaseTitleList PubMed
MEDLINE - Academic

CrossRef
Publicly Available Content Database


Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Open Access Full Text
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
EISSN 2079-4991
ExternalDocumentID oai_doaj_org_article_d387db307f364445bc7f5d18f0de5c9d
PMC12029605
A837782349
40278472
10_3390_nano15080607
Genre Journal Article
Review
GroupedDBID 53G
5VS
8FE
8FG
8FH
AADQD
AAFWJ
AAHBH
AAYXX
ABJCF
ADBBV
ADMLS
AENEX
AFKRA
AFPKN
AFZYC
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BBNVY
BCNDV
BENPR
BGLVJ
BHPHI
CCPQU
CITATION
D1I
GROUPED_DOAJ
HCIFZ
HYE
I-F
IAO
ITC
KB.
KQ8
LK8
M7P
MODMG
M~E
OK1
PDBOC
PGMZT
PHGZM
PHGZT
PIMPY
PROAC
RPM
NPM
PQGLB
7QF
7QO
7QQ
7SC
7SE
7SP
7SR
7TA
7TB
7U5
8BQ
8FD
ABUWG
AZQEC
DWQXO
F28
FR3
GNUQQ
H8D
H8G
JG9
JQ2
KR7
L7M
L~C
L~D
P64
PKEHL
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
PUEGO
ID FETCH-LOGICAL-c477t-c14be13e3fe66ecda3b357f57c427f27bd77a9521e18607fb800321fb8c8a71c3
IEDL.DBID BENPR
ISSN 2079-4991
IngestDate Wed Aug 27 01:29:03 EDT 2025
Thu Aug 21 18:26:46 EDT 2025
Fri Jul 11 18:30:02 EDT 2025
Fri Jul 25 11:44:50 EDT 2025
Tue Jul 01 05:40:54 EDT 2025
Mon Jul 21 05:45:45 EDT 2025
Tue Jul 01 05:11:38 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 8
Keywords automated reactors
continuous flow platform
plasmonic nanoparticles
Language English
License https://creativecommons.org/licenses/by/4.0
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c477t-c14be13e3fe66ecda3b357f57c427f27bd77a9521e18607fb800321fb8c8a71c3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
These authors contributed equally to this work.
ORCID 0000-0002-9079-5307
OpenAccessLink https://www.proquest.com/docview/3194634957?pq-origsite=%requestingapplication%
PMID 40278472
PQID 3194634957
PQPubID 2032354
ParticipantIDs doaj_primary_oai_doaj_org_article_d387db307f364445bc7f5d18f0de5c9d
pubmedcentral_primary_oai_pubmedcentral_nih_gov_12029605
proquest_miscellaneous_3194656891
proquest_journals_3194634957
gale_infotracacademiconefile_A837782349
pubmed_primary_40278472
crossref_primary_10_3390_nano15080607
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2025-04-15
PublicationDateYYYYMMDD 2025-04-15
PublicationDate_xml – month: 04
  year: 2025
  text: 2025-04-15
  day: 15
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Nanomaterials (Basel, Switzerland)
PublicationTitleAlternate Nanomaterials (Basel)
PublicationYear 2025
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
References Pinho (ref_29) 2021; 11
Britton (ref_38) 2017; 23
Alharbi (ref_19) 2021; 3
Jackson (ref_20) 2025; 10
ref_11
ref_10
Jellicoe (ref_17) 2022; 13
Yoo (ref_28) 2024; 34
Liu (ref_24) 2022; 18
Taylor (ref_4) 2023; 123
Joseph (ref_35) 2024; 6
Wu (ref_32) 2025; 16
Bui (ref_34) 2024; 5
ref_15
Seifert (ref_8) 2024; 16
Manson (ref_25) 2021; 80
Clayton (ref_2) 2023; 135
Karthik (ref_21) 2022; 299
Hall (ref_31) 2021; 57
Britton (ref_39) 2017; 46
Truong (ref_13) 2024; 332
Adamo (ref_36) 2016; 352
Khositanon (ref_16) 2020; 10
Mitchell (ref_7) 2021; 20
Clayton (ref_3) 2023; 3
Kioumourtzoglou (ref_5) 2024; 9
Schweidtmann (ref_22) 2018; 352
Jellicoe (ref_37) 2022; 5
Jiang (ref_14) 2022; 8
Liu (ref_6) 2025; 25
ref_1
Salley (ref_26) 2020; 11
Ren (ref_30) 2021; 7
Tao (ref_33) 2021; 31
Gaetano (ref_9) 2016; 16
ref_27
Clayton (ref_23) 2022; 7
Jellicoe (ref_18) 2025; 21
Pu (ref_40) 2020; 7
Pokrajac (ref_12) 2021; 15
References_xml – volume: 7
  start-page: 55
  year: 2021
  ident: ref_30
  article-title: Two-step machine learning enables optimised nanoparticle synthesis
  publication-title: NPJ Comput. Mater.
  doi: 10.1038/s41524-021-00520-w
– volume: 10
  start-page: 511
  year: 2025
  ident: ref_20
  article-title: Self-optimising continuous-flow hydrothermal reactor for nanoparticle synthesis
  publication-title: React. Chem. Eng.
  doi: 10.1039/D4RE00339J
– volume: 5
  start-page: 11586
  year: 2022
  ident: ref_37
  article-title: Coiling of Single-Walled Carbon Nanotubes via Selective Topological Fluid Flow: Implications for Sensors
  publication-title: ACS Appl. Nano Mater.
  doi: 10.1021/acsanm.2c02579
– volume: 10
  start-page: 353
  year: 2020
  ident: ref_16
  article-title: Continuous-flow purification of silver nanoparticles and its integration with flow synthesis
  publication-title: J. Flow Chem.
  doi: 10.1007/s41981-020-00084-8
– volume: 13
  start-page: 3375
  year: 2022
  ident: ref_17
  article-title: Vortex fluidic induced mass transfer across immiscible phases
  publication-title: Chem Sci.
  doi: 10.1039/D1SC05829K
– volume: 6
  start-page: 1202
  year: 2024
  ident: ref_35
  article-title: Vortex fluidic regulated phospholipid equilibria involving liposomes down to sub-micelle size assemblies
  publication-title: Nanoscale Adv.
  doi: 10.1039/D3NA01080E
– volume: 46
  start-page: 1250
  year: 2017
  ident: ref_39
  article-title: Multi-step continuous-flow synthesis
  publication-title: Chem. Soc. Rev.
  doi: 10.1039/C6CS00830E
– ident: ref_11
  doi: 10.3390/molecules28186624
– volume: 332
  start-page: 103263
  year: 2024
  ident: ref_13
  article-title: Precision-engineered metal and metal-oxide nanoparticles for biomedical imaging and healthcare applications
  publication-title: Adv. Colloid Interface Sci.
  doi: 10.1016/j.cis.2024.103263
– volume: 16
  start-page: 1473
  year: 2025
  ident: ref_32
  article-title: Self-driving lab for the photochemical synthesis of plasmonic nanoparticles with targeted structural and optical properties
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-025-56788-9
– volume: 5
  start-page: 2300397
  year: 2024
  ident: ref_34
  article-title: A Proportional–Integral Feedback Controlled Automatic Flow Chemistry System to Produce On-Demand AgAu Alloy Nanoboxes
  publication-title: Small Struct.
  doi: 10.1002/sstr.202300397
– ident: ref_27
  doi: 10.1038/s41598-022-09774-w
– volume: 20
  start-page: 101
  year: 2021
  ident: ref_7
  article-title: Engineering precision nanoparticles for drug delivery
  publication-title: Nat. Rev. Drug Discov.
  doi: 10.1038/s41573-020-0090-8
– volume: 31
  start-page: 2106725
  year: 2021
  ident: ref_33
  article-title: Self-Driving Platform for Metal Nanoparticle Synthesis: Combining Microfluidics and Machine Learning
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.202106725
– volume: 16
  start-page: 19284
  year: 2024
  ident: ref_8
  article-title: Continuous flow synthesis and simulation-supported investigation of tunable plasmonic gold patchy nanoparticles
  publication-title: Nanoscale
  doi: 10.1039/D4NR02516D
– volume: 8
  start-page: eabo2626
  year: 2022
  ident: ref_14
  article-title: An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials
  publication-title: Sci. Adv.
  doi: 10.1126/sciadv.abo2626
– volume: 11
  start-page: 2100918
  year: 2021
  ident: ref_29
  article-title: Dial-A-Particle: Precise Manufacturing of Plasmonic Nanoparticles Based on Early Growth Information—Redefining Automation for Slow Material Synthesis
  publication-title: Adv. Energy Mater.
  doi: 10.1002/aenm.202100918
– volume: 25
  start-page: 754
  year: 2025
  ident: ref_6
  article-title: Designing Hybrid Plasmonic Superlattices with Spatially Confined Responsive Heterostructural Units
  publication-title: Nano Lett.
  doi: 10.1021/acs.nanolett.4c05072
– volume: 3
  start-page: e202300021
  year: 2023
  ident: ref_3
  article-title: Recent Developments in Reactor Automation for Multistep Chemical Synthesis
  publication-title: Chem. Methods
  doi: 10.1002/cmtd.202300021
– volume: 18
  start-page: 2106580
  year: 2022
  ident: ref_24
  article-title: Microfluidic Nanoparticles for Drug Delivery
  publication-title: Small
  doi: 10.1002/smll.202106580
– volume: 23
  start-page: 13270
  year: 2017
  ident: ref_38
  article-title: Vortex Fluidic Chemical Transformations
  publication-title: Chem. Eur. J.
  doi: 10.1002/chem.201700888
– volume: 299
  start-page: 134427
  year: 2022
  ident: ref_21
  article-title: Development of lab-on-chip biosensor for the detection of toxic heavy metals: A review
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2022.134427
– volume: 80
  start-page: 865
  year: 2021
  ident: ref_25
  article-title: MVMOO: Mixed variable multi-objective optimisation
  publication-title: J. Glob. Optim.
  doi: 10.1007/s10898-021-01052-9
– ident: ref_1
  doi: 10.1038/s41598-020-58580-9
– ident: ref_15
  doi: 10.2139/ssrn.5044345
– volume: 34
  start-page: 2312561
  year: 2024
  ident: ref_28
  article-title: Bespoke Metal Nanoparticle Synthesis at Room Temperature and Discovery of Chemical Knowledge on Nanoparticle Growth via Autonomous Experimentations
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.202312561
– volume: 352
  start-page: 61
  year: 2016
  ident: ref_36
  article-title: On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
  publication-title: Science
  doi: 10.1126/science.aaf1337
– ident: ref_10
  doi: 10.26434/chemrxiv-2025-tx4tq
– volume: 7
  start-page: 987
  year: 2022
  ident: ref_23
  article-title: Automated multi-objective reaction optimisation: Which algorithm should I use?
  publication-title: React. Chem. Eng.
  doi: 10.1039/D1RE00549A
– volume: 3
  start-page: 3064
  year: 2021
  ident: ref_19
  article-title: Sub-micron moulding topological mass transport regimes in angled vortex fluidic flow
  publication-title: Nanoscale Adv.
  doi: 10.1039/D1NA00195G
– volume: 11
  start-page: 2771
  year: 2020
  ident: ref_26
  article-title: A nanomaterials discovery robot for the Darwinian evolution of shape programmable gold nanoparticles
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-020-16501-4
– volume: 7
  start-page: 191204
  year: 2020
  ident: ref_40
  article-title: Liquid cell transmission electron microscopy and its applications
  publication-title: R. Soc. Open Sci.
  doi: 10.1098/rsos.191204
– volume: 57
  start-page: 4926
  year: 2021
  ident: ref_31
  article-title: Autonomous optimisation of a nanoparticle catalysed reduction reaction in continuous flow
  publication-title: Chem. Commun.
  doi: 10.1039/D1CC00859E
– volume: 16
  start-page: 3069
  year: 2016
  ident: ref_9
  article-title: Gold and Silver Nanoparticles for Applications in Theranostics
  publication-title: Curr. Top. Med. Chem.
  doi: 10.2174/1568026616666160715163346
– volume: 15
  start-page: 18608
  year: 2021
  ident: ref_12
  article-title: Nanotechnology for a Sustainable Future: Addressing Global Challenges with the International Network4Sustainable Nanotechnology
  publication-title: ACS Nano
  doi: 10.1021/acsnano.1c10919
– volume: 21
  start-page: 2403529
  year: 2025
  ident: ref_18
  article-title: Continuous Flow Synthesis of Copper Oxide Nanoparticles Enabling Rapid Screening of Synthesis-Structure-Property Relationships
  publication-title: Small
  doi: 10.1002/smll.202403529
– volume: 135
  start-page: e202214511
  year: 2023
  ident: ref_2
  article-title: Bayesian Self-Optimization for Telescoped Continuous Flow Synthesis
  publication-title: Angew. Chem.
  doi: 10.1002/ange.202214511
– volume: 9
  start-page: 1364
  year: 2024
  ident: ref_5
  article-title: Nanomaterials as a Service (NaaS) concept: On-demand protocols for volume synthesis of nanomaterials
  publication-title: Nanoscale Horiz.
  doi: 10.1039/D4NH00174E
– volume: 123
  start-page: 3089
  year: 2023
  ident: ref_4
  article-title: A Brief Introduction to Chemical Reaction Optimization
  publication-title: Chem. Rev.
  doi: 10.1021/acs.chemrev.2c00798
– volume: 352
  start-page: 277
  year: 2018
  ident: ref_22
  article-title: Machine learning meets continuous flow chemistry: Automated optimization towards the Pareto front of multiple objectives
  publication-title: Chem. Eng. J.
  doi: 10.1016/j.cej.2018.07.031
SSID ssj0000913853
Score 2.2888877
SecondaryResourceType review_article
Snippet Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses...
SourceID doaj
pubmedcentral
proquest
gale
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage 607
SubjectTerms Artificial intelligence
automated reactors
Automation
Continuous flow
continuous flow platform
Control theory
Discovery and exploration
Fabrication
Feedback loops
Learning strategies
Mechanization
Nanomaterials
Nanoparticles
Outer space
plasmonic nanoparticles
Plasmonics
Reactors
Real time
Review
Space exploration
Spectrum analysis
Synthesis
Technology application
SummonAdditionalLinks – databaseName: DOAJ Open Access Full Text
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEBYlp_YQ-khSt0lRIaUnk9XbPm5KQii0lJBAbkIvkxzqLc3u_-83trN46aGXnrxYthnNeDTfrMbfMHYqA4FS2jMswta6JFvHpEQdLGKJwM8g6Xvnb9_t1a3-emfuZq2-qCZspAceFXeWVeNyxJvYKYRubWJyncmi6Ra5mNRmWn0R82bJ1LAGt0IhEI2V7gp5_Vkf-hVxny8sdY6dxaCBqv_vBXkWkXarJWfh5_Il259wI1-O8r5iz0r_mr2YsQm-YReAgLiZz-qAHvlDz5eb9Qq4tGR-XcbuOhxIlf8Abv5JxLgcKyxS56lC7oDdXl7cfLmqpy4JddLOreskdCz0X2ZXrC0pBxWVgY5c0tJ10sXsXGgRpYtoMPcuAiIqKXBMTXAiqUO216_68pbxZDudYo7JxKIbOGcXJR6e2pItHL2p2KcnvflfIxmGRxJB-vVz_VbsnJS6vYYorIcTMKyfpuP_ZdiKfSaTeHI06D2F6XsBiEqUVX6J1BrwRum2YsdPVvOTBz56SK8tBg2k-bgdhu_Qhkjoy2ozXWNs04qKHY1G3sqshy1ZJyvW7Jh_Z1K7I_3D_cDPLeRCIjE07_6HGt6z55JaDhO9pDlme-vfm3ICHLSOH4ZX_g-YtAgq
  priority: 102
  providerName: Directory of Open Access Journals
Title Recent Developments in Automated Reactors for Plasmonic Nanoparticles
URI https://www.ncbi.nlm.nih.gov/pubmed/40278472
https://www.proquest.com/docview/3194634957
https://www.proquest.com/docview/3194656891
https://pubmed.ncbi.nlm.nih.gov/PMC12029605
https://doaj.org/article/d387db307f364445bc7f5d18f0de5c9d
Volume 15
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9swDCbW9LIdhnVPd12gARt2MhrJsqScinRIWgxYURQr0JtgPbz2MLtrkv9f0lZSBwN2ihE7gURK5EeK_gjwRVQESunMMHKVy-hV7nzB80qhL-F4WQl63_nnhTq_lj9uypuUcFumssqNTewMdWg95ciPcalIVSCc1yf3f3PqGkWnq6mFxh7sowk2ZgT7p_OLy6ttloVYL9Eh9RXvBcb3x03VtMSBPlHUQXbgizrK_n8N88Az7VZNDtzQ4hW8TPiRzXqFH8Cz2LyGFwNWwTcwRyiIP2aDeqAlu2vYbL1qEZ_GwK5i32WHIWJll4if_xBBLkNLiyF0qpR7C9eL-a_v53nqlpB7qfUq91y6SDnNOioVfagKV5S6LrWXQtdCu6B1NUVvHbnBudcOoWIhOH56U2nui3cwatomfgDmVS29C86XLkqDkq-dwD_30xgUbniTwdeN3Ox9T4phMZgg-dqhfDM4JaFunyEq6-6L9uG3TdOxoTA6ODQ1dYHYTJbO46ADN_UkxNJPQwbfSCWWNhzK3VfpvQEcKlFX2RmG2AhzcGlkcLTRmk07cWmf1k0Gn7e3cQ_RwUjVxHadnimVmfIM3vdK3o5ZdkezWmRgdtS_M6ndO83dbcfTzcVEYIBYHv5_XB_huaCmwkQgWR7BaPWwjp8Q6azcGPbM4mycFvW4yxc8AgRWAm0
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VcgAOiDehBYxExSlq7Dh29oCqBbps6UMItVJvbvwI9EBSurtC_VP8xs7ksWSFxK2nRHES2TPjmW_s8QzAW1EQKKU9w8BVLINTsXUpjwuFtoTjbSHovPPhkZqeyC-n2eka_OnPwlBYZa8TG0Xta0dr5NsoKlKlCOf1zsWvmKpG0e5qX0KjFYv9cPUbXbbZ-71PyN8tISa7xx-ncVdVIHZS63nsuLSB1v7KoFRwvkhtmuky004KXQptvdbFCK1a4LlKdGkRUqWC49XlheYuxf_egtsyRUtOJ9Mnn5drOpRjE81fG1-P7cl2VVQ1ZVxPFNWrHVi-pkDAv2ZgYAdXYzQHRm_yAO53aJWNW_F6CGuhegT3BjkMH8MuAk_8mA2ij2bsvGLjxbxGNBw8-xbamj4M8TH7imj9J6XjZajX0WHv4vKewMmNUPEprFd1FZ4Dc6qUznrrMhtkjnwurcCfu1HwCtVLHsFWTzdz0abgMOi6EH3NkL4RfCCiLt-hxNnNg_ryu-mGY3yaa29RsZUpIkGZWYed9jwvEx8yN_IRvCOWGJreSHdXdKcUsKuUKMuM0aFHUIWCGMFmzzXTzfuZ-SulEbxZNuOMpW2Yogr1onsnU_mIR_CsZfKyz7LZCNYignyF_SuDWm2pzn80WcG5SAS6o9mL__frNdyZHh8emIO9o_0NuCuonDGlrsw2YX1-uQgvEWPN7atGsBmc3fRMugY-tTw-
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVEJwQLwxFDASFScr3od37QNCKU3UUoiiikq9Ge_D0AN2aRIh_hq_jhk_giMkbj0lih1rPTM7883u7DcAr3lBoJT2DD1TkfRWRcYKFhUKYwnDrwWn886f5uroTH44T8534Hd_FobKKnuf2DhqV1taIx-jqUglEM7rcdmVRSwOZ-8uf0TUQYp2Wvt2Gq2JnPhfPzF9W749PkRd73M-m35-fxR1HQYiK7VeRZZJ42kdsPRKeesKYUSiy0RbyXXJtXFaFxlGOM9SFevSILwSnOGnTQvNrMDn3oBdTVnRCHYPpvPF6WaFhxg3MRi21fZCZPG4Kqqa-NdjRd1rB3GwaRfwb1AYRMXtis1BCJzdhTsddg0nrbHdgx1f3YfbA0bDBzBFGIp_Dge1SMvwogon61WN2Ni78NS3HX5CRMvhArH7dyLnDdHLY_reVek9hLNrkeMjGFV15Z9AaFUprXHGJsbLFLVeGo4Pt5l3Cp1NGsB-L7f8siXkyDGRIfnmQ_kGcEBC3dxDNNrND_XV17x7ndyJVDuDbq4UiAtlYiwO2rG0jJ1PbOYCeEMqyWmyo9xt0Z1ZwKESbVY-wfQeIRaaZQB7vdbyzgss8782G8CrzWWcv7QpU1S-Xnf3JCrNWACPWyVvxiybbWHNA0i31L_1UttXqotvDUc44zHH5DR5-v9xvYSbOIvyj8fzk2dwi1NvY-KxTPZgtLpa--cIuFbmRWfZIXy57sn0B_2WQdA
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Recent+Developments+in+Automated+Reactors+for+Plasmonic+Nanoparticles&rft.jtitle=Nanomaterials+%28Basel%2C+Switzerland%29&rft.au=He%2C+Shan&rft.au=Luo%2C+Tong&rft.au=Chen%2C+Xiao%27e&rft.au=Young%2C+David+James&rft.date=2025-04-15&rft.issn=2079-4991&rft.eissn=2079-4991&rft.volume=15&rft.issue=8&rft_id=info:doi/10.3390%2Fnano15080607&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2079-4991&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2079-4991&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2079-4991&client=summon