Genetic association testing using the GENESIS R/Bioconductor package

• Published in: Bioinformatics (Oxford, England) Vol. 35; no. 24; pp. 5346 - 5348
• Main Authors: Gogarten, Stephanie M, Sofer, Tamar, Chen, Han, Yu, Chaoyu, Brody, Jennifer A, Thornton, Timothy A, Rice, Kenneth M, Conomos, Matthew P
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 15.12.2019
• Subjects: Applications Notes; Genetic Testing; Genome; Genomics; Sequence Analysis; Software

The Genomic Data Storage (GDS) format provides efficient storage and retrieval of genotypes measured by microarrays and sequencing. We developed GENESIS to perform various single- and aggregate-variant association tests using genotype data stored in GDS format. GENESIS implements highly flexible mix...