Usefulness of a newly developed high-speed polymerase chain reaction analysis system for the diagnosis of Clostridioides difficile infection

• Published in: Journal of Infection and Chemotherapy Vol. 27; no. 5; pp. 715 - 721
• Main Authors: Furukawa, Keitaro, Mitsutake, Hiroshi, Aso, Ryoko, Sekizawa, Ryuichi, Okanda, Takashi, Hayashi, Kuniyoshi, Matsumoto, Tetsuya, Nakamura, Shigeki
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.05.2021; Elsevier BV
• Subjects: Bacterial Proteins; Bacterial Toxins; Clostridioides; Clostridioides difficile; Clostridium Infections; Feces; High-speed PCR; Humans; Immunoenzyme Techniques; Nucleic acid amplification tests; Polymerase Chain Reaction; Real-time PCR; Sensitivity and Specificity; High-speed PCR; Clostridioides difficile; Real-time PCR; Nucleic acid amplification tests

The incidence of Clostridioides difficile infection (CDI) has been continuously increasing and thereby became an important issue worldwide. Appropriate diagnosis, management, and infection control are required for patients with CDI. Enzyme immunoassay (EIA) is a widely used standard diagnostic tool...