The melanocyte lineage in development and disease

• Published in: Development (Cambridge) Vol. 142; no. 4; pp. 620 - 632
• Main Authors: Mort, Richard L, Jackson, Ian J, Patton, E Elizabeth
• Format: Journal Article
• Language: English
• Published: England The Company of Biologists 15.02.2015
• Subjects: Animals; Danio rerio; Humans; Melanocytes - cytology; Melanocytes - metabolism; Melanoma - metabolism; Melanoma - pathology; Microphthalmia-Associated Transcription Factor - metabolism; Neural Crest - cytology; Reviews; Stem Cells - cytology; Stem Cells - metabolism; MITF; Neural crest; Melanoma; Stem cells

Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations within the skin and hair follicles, and to ot...