Divergent Impact of Actin Isoforms on Division of Epithelial Cells

• Published in: Biochemistry (Moscow) Vol. 85; no. 9; pp. 1072 - 1081
• Main Authors: Shagieva, G. S., Alieva, I. B., Chaponnier, C., Dugina, V. B.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.09.2020; Springer
• Subjects: Actin; Actins - metabolism; Biochemistry; Biomedical and Life Sciences; Biomedicine; Bioorganic Chemistry; Cells, Cultured; Comparative analysis; Cytokinesis; Cytoplasm - metabolism; Humans; Keratinocytes - cytology; Keratinocytes - metabolism; Life Sciences; Microbiology; Microtubules - metabolism; Mitosis; Muscle proteins; Protein Isoforms; RNA; Tubulins; Germany; cell division; microtubules; cytoplasmic actin; mitosis

We investigated distribution and functions of beta- and gamma-cytoplasmic actins (CYAs) at different stages of non-neoplastic epithelial cell division using laser scanning microscopy (LSM). Here, we demonstrated that beta- and gamma-CYAs are spatially segregated in the early prophase, anaphase, telo...