Frequency and Time Domain Analysis of EEG Based Auditory Evoked Potentials to Detect Binaural Hearing in Noise

• Published in: Journal of clinical medicine Vol. 12; no. 13; p. 4487
• Main Authors: Ignatious, Eva, Azam, Sami, Jonkman, Mirjam, De Boer, Friso
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 04.07.2023; MDPI
• Subjects: Analysis; Auditory evoked response; Binaural hearing; Child development; Clinical medicine; Cognition & reasoning; Cognitive development; Diagnosis; Ears & hearing; Electroencephalography; Health aspects; Hearing loss; Hearing protection; Investigations; Localization; Measurement; Noise; Quality of life; Risk factors; Sound; Australia; frequency domain analysis; homophasic; auditory evoked potential (AEP); time domain analysis; antiphasic; electroencephalogram (EEG)
• DOI: 10.3390/jcm12134487
• ISSN: 2077-0383

Hearing loss is a prevalent health issue that affects individuals worldwide. Binaural hearing refers to the ability to integrate information received simultaneously from both ears, allowing individuals to identify, locate, and separate sound sources. Auditory evoked potentials (AEPs) refer to the electrical responses that are generated within any part of the auditory system in response to auditory stimuli presented externally. Electroencephalography (EEG) is a non-invasive technology used for the monitoring of AEPs. This research aims to investigate the use of audiometric EEGs as an objective method to detect specific features of binaural hearing with frequency and time domain analysis techniques. Thirty-five subjects with normal hearing and a mean age of 27.35 participated in the research. The stimuli used in the current study were designed to investigate the impact of binaural phase shifts of the auditory stimuli in the presence of noise. The frequency domain and time domain analyses provided statistically significant and promising novel findings. The study utilized Blackman windowed 18 ms and 48 ms pure tones as stimuli, embedded in noise maskers, of frequencies 125 Hz, 250 Hz, 500 Hz, 750 Hz, 1000 Hz in homophasic (the same phase in both ears) and antiphasic (180-degree phase difference between the two ears) conditions. The study focuses on the effect of phase reversal of auditory stimuli in noise of the middle latency response (MLR) and late latency response (LLR) regions of the AEPs. The frequency domain analysis revealed a significant difference in the frequency bands of 20 to 25 Hz and 25 to 30 Hz when elicited by antiphasic and homophasic stimuli of 500 Hz for MLRs and 500 Hz and 250 Hz for LLRs. The time domain analysis identified the Na peak of the MLR for 500 Hz, the N1 peak of the LLR for 500 Hz stimuli and the P300 peak of the LLR for 250 Hz as significant potential markers in detecting binaural processing in the brain.