Native-state imaging of calcifying and noncalcifying microalgae reveals similarities in their calcium storage organelles

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 115; no. 43; pp. 11000 - 11005
• Main Authors: Gal, Assaf, Sorrentino, Andrea, Kahil, Keren, Pereiro, Eva, Faivre, Damien, Scheffel, André
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 23.10.2018
• Subjects: Acids - metabolism; Adaptability; Algae; Biological Sciences; Calcification; Calcification, Physiologic - physiology; Calcite; Calcium; Calcium - metabolism; Calcium carbonate; Calcium Carbonate - metabolism; Calcium homeostasis; Calcium sequestration; Calcium signalling; Chemical composition; Chlamydomonas reinhardtii; Chlamydomonas reinhardtii - metabolism; Cytoplasm; Haptophyta - metabolism; Homeostasis; Homeostasis - physiology; Life Sciences; Microalgae - metabolism; Mineralization; Minerals - metabolism; Oceans and Seas; Organelles; Organelles - metabolism; Organic chemistry; Phosphorus - metabolism; Physical Sciences; Polyphosphates; Polyphosphates - metabolism; Storage; Tomography; Volutin granules; acidocalcisome; coccolithophore; cryo–X-ray tomography; biomineralization; intracellular calcium store

Calcium storage organelles are common to all eukaryotic organisms and play a pivotal role in calcium signaling and cellular calcium homeostasis. In most organelles, the intraorganellar calcium concentrations rarely exceed micromolar levels. Acidic organelles called acidocalcisomes, which concentrate...