An open label, single arm, prospective clinical study to evaluate liver safety and tolerability of PUREMERIC™ (standardized extract from Curcuma longa) in healthy subjects

• Published in: Toxicology reports Vol. 8; pp. 1955 - 1959
• Main Authors: HV, Sudeep, V Thomas, Jestin, HS, Vasavi, K, Shyamprasad
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.01.2021; Elsevier
• Subjects: alanine transaminase; alkaline phosphatase; aspartate transaminase; bilirubin; blood serum; Cholestatic hepatitis; Curcumin; gamma-glutamyltransferase; Healthy subjects; hepatitis; lactate dehydrogenase; liver; liver function; polyphenols; Regular; Safety; toxicology; Turmeric; Turmeric; Healthy subjects; Curcumin; Cholestatic hepatitis; Safety

[Display omitted] •PUREMERIC™ is a standardized turmeric extract containing not less than 95 % curcuminoids.•12-week supplementation of 1g/day of PUREMERIC did not alter the liver function parameters of healthy human volunteers.•The safety of the extract was further confirmed by the insignificant ch...