The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells - Man, Kevin; Miasari, Maria; Shi, Wei; Xin, Annie; Henstridge, Darren C; Preston, Simon; Pellegrini, Marc; Belz, Gabrielle T; Smyth, Gordon K; Febbraio, Mark A; Nutt, Stephen L; Kallies, Axel (Nature immunology, 2013)
Keywords: 631/250/248; 631/250/2502/248; Animals; Biomedicine; CD4-Positive T-Lymphocytes - immunology; CD4-Positive T-Lymphocytes - metabolism; CD4-Positive T-Lymphocytes - virology; CD8-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - metabolism; CD8-Positive T-Lymphocytes - virology; Cell Differentiation; Cell Proliferation; Clone Cells; Gene Expression Regulation; Genetic aspects; Glucose metabolism; Humans; Immunology; Infectious Diseases; Influenza A Virus, H3N2 Subtype - immunology; Interferon Regulatory Factors - genetics; Interferon Regulatory Factors - immunology; Interferon Regulatory Factors - metabolism; Mice; Mice, Transgenic; Orthomyxoviridae Infections - immunology; Orthomyxoviridae Infections - metabolism; Orthomyxoviridae Infections - virology; Physiological aspects; Receptors, Antigen, T-Cell - genetics; Receptors, Antigen, T-Cell - immunology; Receptors, Antigen, T-Cell - metabolism; T cells; T-Lymphocyte Subsets - immunology; T-Lymphocyte Subsets - metabolism; T-Lymphocyte Subsets - virology; Transcription factors; Transcription, Genetic; Australia