Thioredoxin-1 and Correlations of the Plasma Cytokines Regarding Aortic Valve Stenosis Severity

• Published in: Biomedicines Vol. 9; no. 8; p. 1041
• Main Authors: Tretjakovs, Peteris, Lurins, Juris, Svirskis, Simons, Gersone, Gita, Lurina, Dace, Rozenberga, Ulla, Blumfelds, Leons, Bahs, Guntis, Lejnieks, Aivars, Mackevics, Vitolds
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 18.08.2021; MDPI
• Subjects: Angiopoietin; Antioxidants; Aortic valve; aortic valve stenosis; Atherosclerosis; Biomarkers; Body mass index; Cardiovascular disease; Correlation analysis; Cytokines; Enzymes; Fibroblast growth factor 2; Fibroblasts; growth factors; Inflammation; Metalloproteinase; myeloperoxidase; Oxidative stress; Patients; Peroxidase; Plasma; Plasma levels; Proteins; Signal transduction; Software; Stenosis; Thioredoxin; thioredoxin-1; Thoracic surgery; Ultrasonic imaging; Vascular endothelial growth factor; United States > US

Aortic valve stenosis (AS) develops not only with a pronounced local inflammatory response, but also oxidative stress is involved. The aim of this study was to evaluate the plasma levels of thioredoxin-1 (TRX1), myeloperoxidase (MPO), chemerin, growth differentiation factor 15 (GDF-15), angiopoietin...