Effects of rivastigmine on gait in patients with neurodegenerative disorders: A systematic review and meta-analysis

• Published in: PloS one Vol. 19; no. 12; p. e0310900
• Main Authors: Shim, Sung Ryul, Kim, Jong-Yeup, Kwon, Kyum-Yil, Shin, Jieun, Lee, Yungjin, Lee, Seon-Min
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 12.12.2024; Public Library of Science (PLoS)
• Subjects: Accidental Falls - prevention & control; Accidental Falls - statistics & numerical data; Alzheimer Disease - complications; Alzheimer Disease - drug therapy; Alzheimer Disease - physiopathology; Alzheimer's disease; Bias; Biology and Life Sciences; Cholinergics; Cholinesterase; Cholinesterase inhibitors; Cholinesterase Inhibitors - pharmacology; Cholinesterase Inhibitors - therapeutic use; Cognitive ability; Collaboration; Dementia; Disturbances; Executive function; Falls; Gait; Gait - drug effects; Gait - physiology; Health services; Humans; Literature reviews; Medicine and Health Sciences; Meta-analysis; Neurodegenerative diseases; Neurodegenerative Diseases - complications; Neurodegenerative Diseases - drug therapy; Neurodegenerative Diseases - physiopathology; Neuroprotective Agents - pharmacology; Neuroprotective Agents - therapeutic use; Parkinson Disease - complications; Parkinson Disease - drug therapy; Parkinson Disease - physiopathology; Parkinson's disease; Patients; Physical Sciences; Research and Analysis Methods; Rivastigmine; Rivastigmine - pharmacology; Rivastigmine - therapeutic use; Searching; Statistical analysis; Systematic review

Gait disturbances are commonly observed in patients with neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and higher-level gait disorders, which are associated with cholinergic deficits. We conducted a systematic review and meta-analysis to investigate the e...