Inhibition of EGFR autophosphorylation plays an important role in the anti-breast cancer efficacy of the dithiocarbamate derivative TM208 - Ji, Xi-wei; Li, Run-tao; Li, Zai-quan; Li, Liang; Shao, Xue-yan; Wang, Si-yuan; Yuan, Yin; Zhou, Tian-yan; Lu, Wei (Acta pharmacologica Sinica, 2014)
Keywords: Animals; Biomedical and Life Sciences; Biomedicine; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; Cell Line, Tumor; Female; Humans; Immunology; Internal Medicine; LC-MS; MCF-7 Cells; Medical Microbiology; Mice; Mice, Inbred BALB C; Mice, Nude; Original; original-article; Pharmacology/Toxicology; Phosphorylation - drug effects; Piperazines - pharmacology; Receptor, Epidermal Growth Factor - antagonists & inhibitors; Receptor, Epidermal Growth Factor - metabolism; Vaccine; Western印迹; 二硫代氨基甲酸; 人乳腺癌细胞; 异种移植; 自磷酸化; 衍生物; 表皮生长因子受体; TM208; ERK1/2; tumor xenograft nude mice; breast cancer; dithiocarbamate; tyrosine kinase inhibitor; phosphorylation; EGFR