Comparison of plasma aldosterone measured by chemiluminescence immunoassay and liquid chromatography-tandem mass spectrometry in screening test for primary aldosteronism

• Published in: Practical laboratory medicine Vol. 39; p. e00361
• Main Authors: Chen, Wenzhan, Lai, Fenghua, Huang, Xiaoyu, Yu, Shuang, Chen, Nan, Xu, Changliu, Wang, Chenxue, Liang, Shuhui, Li, Yanbing, Xiao, Haipeng, Cao, Xiaopei
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2024; Elsevier
• Subjects: Chemiluminescence immunoassay; Liquid chromatography with tandem mass spectrometry; Original; Primary aldosteronism; Screening test; Chemiluminescence immunoassay; Primary aldosteronism; Screening test; Liquid chromatography with tandem mass spectrometry

Whether chemiluminescence immunoassay (CLIA) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) for plasma aldosterone concentration (PAC) measurement can be used interchangeably in primary aldosteronism (PA) screening is still controversial. The purpose of this study was to compare CLIA...