Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line

• Published in: Nutrition research and practice Vol. 3; no. 4; pp. 259 - 264
• Main Authors: Kim, M.S., Mokpo National University, Muan, Republic of Korea, You, M.K., Mokpo National University, Muan, Republic of Korea, Rhuy, D.Y., Mokpo National University, Muan, Republic of Korea, Kim, Y.J., Korea INSpharm Research Institute, Hwasun, Republic of Korea, Baek, H.Y., Korea INSpharm Research Institute, Hwasun, Republic of Korea, Kim, H.A., Mokpo National University, Muan, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Korea (South) 한국영양학회 01.01.2009; The Korean Nutrition Society and The Korean Society of Community Nutrition
• Subjects: adhesion; ERIOBOTRYA JAPONICA; invasion; MIGRACION; MIGRATION; MMP; Original Research; 생활과학; migration; MMP; Loquat (Eriobotrya japonica); adhesion; invasion

We examined the inhibitory effects of loquat methanol extract on the adhesion, migration, invasion and matrix metalloproteinase (MMP) activities of MDA-MB-231 human breast cancer cell line. Cells were cultured with DMSO or with 10, 25, or 50 ㎍/ml of loquat methanol extract. Both leaf and seed extrac...