A framework for implementation of organ effect models in TOPAS with benchmarks extended to proton therapy

• Published in: Physics in medicine & biology Vol. 60; no. 13; pp. 5037 - 5052
• Main Authors: Ramos-Méndez, J, Perl, J, Schümann, J, Shin, J, Paganetti, H, Faddegon, B
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 07.07.2015
• Subjects: Benchmarking; Endpoint Determination; Monte Carlo; Monte Carlo Method; organ effect; proton therapy; Proton Therapy - methods; Radiation Dosage; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Software; TOPAS

The aim of this work was to develop a framework for modeling organ effects within TOPAS (TOol for PArticle Simulation), a wrapper of the Geant4 Monte Carlo toolkit that facilitates particle therapy simulation. The DICOM interface for TOPAS was extended to permit contour input, used to assign voxels...