The interdependence of mid-trimester blood pressure and glucose levels in shaping fetal growth and neonatal outcomes: implications for risk–benefit assessment and co-management

• Published in: BMC medicine Vol. 23; no. 1; pp. 161 - 13
• Main Authors: Lv, Lijuan, Yang, Jingbo, Li, Linjie, Huang, Chuanyi, Shi, Huihua, Fang, Yiwen, Zuo, Lushu, Liu, Ting, Duan, Hongli, Wen, Jiying, Yang, Qing, Henry, Amanda, Han, Cha, Yin, Aihua, Zhou, Xin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14.03.2025; BioMed Central; BMC
• Subjects: Adjustment; Adult; Birth weight; Births; Blood Glucose - analysis; Blood pressure; Blood Pressure - physiology; Body mass index; Dextrose; Diabetes; Drug dosages; Fasting plasma glucose; Female; Fetal Development - physiology; Fetus; Fetuses; Gestational age; Gestational diabetes; Glucose; Growth; Hospitals; Humans; Hyperglycemia; Hypertension; Hypertensive disorders in pregnancy; Hypoglycemia; Infant, Newborn; Infant, Small for Gestational Age; Infants (Newborn); Large-for-gestational-age infants; Medical research; Medicine, Experimental; Neonates; Physiological aspects; Polynomials; Preeclampsia; Pregnancy; Pregnancy Trimester, Second - blood; Quantiles; Regression analysis; Risk Assessment; Small for gestational age; Small-for-gestational age infants; Statistical analysis; Stillbirth; Variables; Womens health; China; Neonatal complications; Large-for-gestational-age infants; Fasting plasma glucose; Hypertensive disorders in pregnancy; Blood pressure; Gestational diabetes; Small-for-gestational age infants

Maternal hypertension and hyperglycemia are closely related but have distinct impacts on fetal growth and are managed independently. How the interdependence of blood pressure (BP) and glucose levels quantitatively influences risk patterns for abnormal fetal growth and neonatal complications remains...