The Efficacy of Percutaneous Patent Foramen Ovale Closure on Migraine: a Meta-Analysis of Randomized Controlled Trials and Observational Studies

• Published in: BioMed research international Vol. 2021; no. 1; p. 6643266
• Main Authors: Zhang, Quan-Quan, Lu, Jia-Jie, Yan, Man-Yun, Hu, Xiao-Wei, Qin, Yi-Ren, Wang, Da-Peng, Jiang, Jian-Hua, Fang, Qi, Zhao, Hong-Ru
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2021; John Wiley & Sons, Inc
• Subjects: Aspirin; Asymptomatic; Bias; Cardiac Catheterization; Care and treatment; Clinical trials; Foramen Ovale, Patent - complications; Foramen Ovale, Patent - physiopathology; Foramen Ovale, Patent - surgery; Headache; Headaches; Humans; Meta-analysis; Methods; Migraine; Migraine with Aura - etiology; Migraine with Aura - physiopathology; Migraine with Aura - surgery; Observational studies; Observational Studies as Topic; Patent foramen ovale; Patient outcomes; Randomized Controlled Trials as Topic; Reduction; Risk factors; Septal Occluder Device; Statistical analysis; Stroke; Subgroups; Surgery; China

Objectives. Whether patent foramen ovale (PFO) closure is effective on migraine is controversial. This article was aimed at assessing the efficacy of PFO closure on migraine based on randomized controlled trials (RCTs) and observational studies. Methods. We searched PubMed, Embase, and Cochrane data...