Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

• Published in: Chemosphere (Oxford) Vol. 244; p. 125492
• Main Authors: Li, Boqing, Ding, Yunfei, Cheng, Xue, Sheng, Dandan, Xu, Zheng, Rong, Qianyu, Wu, Yulong, Zhao, Huilin, Ji, Xiaofei, Zhang, Ying
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2020
• Subjects: animal models; Animals; Bacteria - drug effects; blood serum; colon; Colon - drug effects; duodenum; Dysbiosis; flora; Gastrointestinal Microbiome - drug effects; Gut microbiota; Inflammation; Inflammation response; interleukin-1alpha; intestinal microorganisms; Intestines - drug effects; Mice; Mice, Inbred C57BL; Microplastics; Microplastics - toxicity; pollution; Polyethylene; Polyethylene - toxicity; public health; Staphylococcus; Toll-like receptor 4; Gut microbiota; Polyethylene; Microplastics; Mice; Inflammation response

Environmental pollution caused by plastics has become a public health problem. However, the effect of microplastics on gut microbiota, inflammation development and their underlying mechanisms are not well characterized. In the present study, we assessed the effect of exposure to different amounts of...