Inhibition Peroxiredoxin‐2 by Capsaicin Ameliorates Rheumatoid Arthritis via ROS‐Mediated Apoptosis in Fibroblast‐Like Synoviocytes

• Published in: MedComm (2020) Vol. 6; no. 6; pp. e70209 - n/a
• Main Authors: He, Hengkai, Hao, Mingjing, Luo, Piao, Chen, Junhui, An, Yehai, Huang, Jingnan, He, Ruiyi, Du, Qingfeng, Zhang, Qian, Wang, Jigang
• Format: Journal Article
• Language: English
• Published: China John Wiley & Sons, Inc 01.06.2025; John Wiley and Sons Inc; Wiley
• Subjects: activity‐based protein profiling; antioxidant; capsaicin; Original; peroxiredoxin‐2; rheumatoid arthritis; activity‐based protein profiling; antioxidant; peroxiredoxin‐2; rheumatoid arthritis; capsaicin

ABSTRACT Rheumatoid arthritis (RA), a prevalent and incurable autoimmune disease globally, is characterized by the immune system attacking the body's own tissues, leading to joint inflammation and damage. Capsaicin (CAP), from Capsicum annuum L., is known for its burning sensation‐inducing prop...