A Light‐Operated Molecular Cable Car for Gated Ion Transport

• Published in: Angewandte Chemie International Edition Vol. 60; no. 27; pp. 14836 - 14840
• Main Authors: Wang, Chenxi, Wang, Shunkang, Yang, Huiting, Xiang, Yanxin, Wang, Xuebin, Bao, Chunyan, Zhu, Linyong, Tian, He, Qu, Da‐Hui
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 25.06.2021; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: artificial ion transport; Azo compounds; Cable cars; Chemistry; Chemistry, Multidisciplinary; Crown ethers; host–guest system; Ion transport; Ions; Isomerization; light-gating; Lipid membranes; Lipids; Membranes; molecular machine; Molecular machines; Physical Sciences; rotaxanes; Science & Technology; molecular machine; artificial ion transport; host– rotaxanes; guest system; light-gating; host-guest system
• ISSN: 1433-7851; 1521-3773; 1521-3773
• DOI: 10.1002/anie.202102838

Inspired by the nontrivial and controlled movements of molecular machines, we report an azobenzene‐based molecular shuttle PR2, which can perform light‐gated ion transport across lipid membranes. The amphiphilicity and membrane‐spanning molecular length enable PR2 to insert into the bilayer membrane...