Flow cytometric analysis of cell‐surface and intracellular antigens in the diagnosis of acute leukemia

• Published in: American journal of hematology Vol. 68; no. 2; pp. 69 - 74
• Main Authors: Paredes‐Aguilera, Rogelio, Romero‐Guzman, Lina, Lopez‐Santiago, Norma, Burbano‐Ceron, Lenny, Camacho‐Del Monte, Ofelia, Nieto‐Martinez, Sandra
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 01.10.2001; Wiley-Liss
• Subjects: Acute Disease; ALL; AML; Antigens - analysis; Antigens, Neoplasm - analysis; Antigens, Surface - analysis; Biological and medical sciences; Biomarkers, Tumor - analysis; Biomarkers, Tumor - immunology; Burkitt Lymphoma - classification; Burkitt Lymphoma - diagnosis; Burkitt Lymphoma - pathology; Cell Lineage - immunology; Child; Cytoplasm - immunology; Diagnosis, Differential; Flow Cytometry; Hematologic and hematopoietic diseases; Humans; immunophenotype; Immunophenotyping; intracellular antigens; Leukemia - classification; Leukemia - diagnosis; Leukemia - pathology; Leukemia, Myeloid - classification; Leukemia, Myeloid - diagnosis; Leukemia, Myeloid - pathology; Leukemia-Lymphoma, Adult T-Cell - classification; Leukemia-Lymphoma, Adult T-Cell - diagnosis; Leukemia-Lymphoma, Adult T-Cell - pathology; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Medical sciences; Human; Flow cytometry; Immunophenotype; Acute; Malignant hemopathy; French American British classification; Cell surface; Antigen; Immunological investigation; Lymphoproliferative syndrome; Diagnosis; Intracellular; Acute lymphocytic leukemia; Acute myelocytic leukemia

To evaluate the usefulness of flow cytometric detection of intracellular antigens (Ags) in establishing proper lineage affiliation and its contribution to the diagnosis of acute leukemia, we studied 100 consecutive patients in whom acute leukemia was diagnosed between January 1997 and July 1998. Imm...