Effect of Lactobacillus rhamnosus on the development of B cells in gut‐associated lymphoid tissue of BALB/c mice

• Published in: Journal of cellular and molecular medicine Vol. 24; no. 15; pp. 8883 - 8886
• Main Authors: Shi, Chun‐wei, Zeng, Yan, Yang, Gui‐lian, Jiang, Yan‐long, Yang, Wen‐tao, Chen, Yi‐qiu, Wang, Jing‐ying, Wang, Jian‐zhong, Kang, Yuan‐huan, Huang, Hai‐bin, Ye, Li‐ping, Cao, Xin, Wang, Chun‐feng
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.08.2020; John Wiley and Sons Inc
• Subjects: activation and antigen presentation; Animals; Antigen presentation; Antigens; B cell development; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; CD40 antigen; CD43 antigen; CD80 antigen; Cell activation; Conflicts of interest; Cytokines; Developmental stages; Enzyme-linked immunosorbent assay; Flow cytometry; Gut-associated lymphoid tissues; Immunoglobulin A; Immunoglobulin D; Immunoglobulin G; Immunoglobulin M; immunoglobulin secretion; Immunoglobulins; Intestinal Mucosa - immunology; Intestinal Mucosa - metabolism; Intestine; Lactobacillus rhamnosus; Lactobacillus rhamnosus - immunology; Lamina propria; Letter to the Editor; Lymphatic system; Lymphocytes; Lymphocytes B; Lymphoid tissue; Major histocompatibility complex; Mammals; Mice; Mice, Inbred BALB C; Mucosal immunity; Peyer's patches; Peyer's Patches - immunology; Peyer's Patches - metabolism; Probiotics; immunoglobulin secretion; B cell development; activation and antigen presentation; Lactobacillus rhamnosus

[...]developmental stages of B cells, that is B220+CD43+IgM−IgD− (pro‐B), B220+CD43−IgM−IgD− (pre‐B), B220+CD43−IgM+IgD− (immature B) and B220+CD43−IgM+IgD+ (mature B), were detected in mouse BM, intestinal lamina propria (LPL) and Peyer's patches (PPs) by flow cytometry. [...]the expression le...