ATG13 restricts viral replication by induction of type I interferon

• Published in: Journal of cellular and molecular medicine Vol. 23; no. 9; pp. 6508 - 6511
• Main Authors: Du, Jiang‐long, Ma, Peng, Wang, Chen, Zeng, Yan, Xue, Yu‐jia, Yang, Xue‐cai, Wan, Xue‐mei, Chang, Fan‐fan, Zhao, Tian‐yu, Jia, Xiao‐ye, Wang, Hai‐zhen, Liu, Jing, Ma, Zhong‐ren, Cao, Xin, Cai, Kui‐zheng
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.09.2019; John Wiley and Sons Inc
• Subjects: Autophagy; Colleges & universities; Expression vectors; Genes; Immunoprecipitation; Infections; Interferon; Interferon regulatory factor; Interferon regulatory factor 3; Kinases; Letter to the Editor; Letters to the Editor; Melanoma; Mitochondria; Plasmids; Proteins; Retinoic acid; RNA-mediated interference; TRAF6 protein; Tumor necrosis factor; Tumor necrosis factor-TNF; Viral infections

Intriguingly, ATG5‐ATG12 positively regulated antiviral NF‐κB and IRF3 signalling during foot‐and‐mouth disease virus infection. [...]Mauthe et al conduct an unbiased RNA interference screen approach to explore unconventional functions of ATG proteins during viral infections. In order to identify po...