The application advances of dendrimers in biomedical field

• Published in: View (Beijing, China) Vol. 4; no. 6
• Main Authors: Li, Longjie, Deng, Yukai, Zeng, Yonghui, Yan, Bei, Deng, Yulian, Zheng, Ziyang, Li, Siqi, Yang, Yuhang, Hao, Jinwei, Xiao, Xianjin, Wang, Xinyu
• Format: Journal Article
• Language: English
• Published: Beijing John Wiley & Sons, Inc 01.12.2023; Wiley
• Subjects: cancer diagnosis; cancer therapy; Computer simulation; Copyright; Cytotoxicity; dendrimers; Methods; Morphology; nanocomposites; PAMAM; Polymerization; Polymers; PPDs; Principles; Proteins; Viruses
• ISSN: 2688-3988; 2688-268X; 2688-268X
• DOI: 10.1002/VIW.20230023

Dendrimers are a family of nano‐sized three‐dimensional polymers with unique dendritic branching structures and compact spherical geometries. In recent years, dendrimers have made a series of breakthroughs in the biomedical field. In this review, we introduce the synthesis principles, modification methods, and new materials designed based on dendrimers; discuss the importance of cytotoxicity of dendrimers for applications; and elaborate on their applications in the field of molecular assembly and cancer diagnosis and treatment. We speculate that in the near future, more new materials based on dendrimers will be applied in the biomedical field. Dendrimers are a family of nano‐sized three‐dimensional polymers which now have attracted more extensive attention in biomedical field. This review provides insights into their synthesis methods, their applications in the field of biomedicine and their applications in cancer diagnosis and treatment. The limitations of dendrimers and the further development prospects are also discussed.