MiR‐101 promotes pain hypersensitivity in rats with chronic constriction injury via the MKP‐1 mediated MAPK pathway - Qiu, Shuang; Liu, Benjuan; Mo, Yanshuai; Wang, Xueqin; Zhong, Lina; Han, Xiao; Mi, Fuli (Journal of cellular and molecular medicine, 2020)
Keywords: Animal models; Animals; Binding sites; Catheters; Cell culture; chronic constriction injury; Constriction; Dorsal horn; Dual Specificity Phosphatase 1 - metabolism; Female; Gene expression; Hypersensitivity; Inflammation; Inflammation - metabolism; Interleukin-1beta - metabolism; Intubation; Kinases; Laboratory animals; Latency; Lipopolysaccharides; MAP kinase; Mechanical stimuli; Microglia - metabolism; Microglial cells; MicroRNAs - metabolism; MicroRNA‐101; miRNA; Mitogen-Activated Protein Kinases - metabolism; mitogen‐activated protein kinase phosphatase 1; Nervous system; Neuralgia; Neuralgia - metabolism; NF-kappa B - metabolism; Original; Pain; pain hypersensitivity; Protein kinase; Rats; Rats, Sprague-Dawley; Rodents; Signal transduction; Signal Transduction - physiology; Spinal cord; Spinal Cord - metabolism; spinal cord microglial cell; Surgery; Tumor necrosis factor; Tumor Necrosis Factor-alpha - metabolism; Tumors; chronic constriction injury; mitogen-activated protein kinase phosphatase 1; MicroRNA-101; pain hypersensitivity; spinal cord microglial cell