Epstein–Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti‐DNA

• Published in: Immunology Vol. 141; no. 2; pp. 276 - 285
• Main Authors: Fattal, Ittai, Shental, Noam, Molad, Yair, Gabrielli, Armando, Pokroy‐Shapira, Elisheva, Oren, Shirly, Livneh, Avi, Langevitz, Pnina, Pauzner, Rachel, Sarig, Ofer, Gafter, Uzi, Domany, Eytan, Cohen, Irun R.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.02.2014; Blackwell Publishing Ltd
• Subjects: Antibodies, Antinuclear - blood; Antibodies, Viral - blood; anti‐dsDNA; autoantibodies; Autoimmune diseases; Epstein-Barr virus; Herpesvirus 4, Human - immunology; Humans; Immune response; Immunoglobulin G - blood; Immunoglobulin M - blood; Lupus Erythematosus, Systemic - immunology; Original; scleroderma; Scleroderma, Systemic - immunology; systemic lupus erythematosus; systemic lupus erythematosus; Epstein-Barr virus; autoantibodies; scleroderma; anti-dsDNA

Summary Systemic lupus erythematosus (SLE) is an autoimmune disease that can attack many different body organs; the triggering event is unknown. SLE has been associated with more than 100 different autoantibody reactivities – anti‐dsDNA is prominent. Nevertheless, autoantibodies to dsDNA occur in on...